Leishmania species: A narrative review on surface proteins with structural aspects involved in host–pathogen interaction

RS Kaushal, N Naik, M Prajapati… - Chemical Biology & …, 2023 - Wiley Online Library
In tropical and subtropical regions of the world, leishmaniasis is endemic and causes a
range of clinical symptoms in people, from severe tegumentary forms (such as cutaneous …

[HTML][HTML] Recent advances on the piezoelectric, electrochemical, and optical biosensors for the detection of protozoan pathogens

M Feyziazar, M Amini, A Jahanban-Esfahlan… - TrAC Trends in …, 2022 - Elsevier
The important protozoan parasites including Plasmodium, Leishmania, Toxoplasma,
Trypanosoma and Giardia have been proved as the main reason initiating and develo** …

An update on small molecule strategies targeting leishmaniasis

S Kapil, PK Singh, OM Silakari - European journal of medicinal chemistry, 2018 - Elsevier
Leishmaniasis is an infectious disease caused by various species of protozoan parasite
known as Leishmania, which is transmitted to its mammalian host via bite of an infected …

Linking membrane fluidity with defective antigen presentation in leishmaniasis

S Pradhan, S Ghosh, S Hussain, J Paul… - Parasite …, 2021 - Wiley Online Library
Hampering‐surface presentation of immunogenic peptides by class I/II MHCs is a key
strategy opted by several intracellular protozoan pathogens including Leishmania to escape …

Leishmania protein KMP-11 modulates cholesterol transport and membrane fluidity to facilitate host cell invasion

A Sannigrahi, S Ghosh, S Pradhan, P Jana… - EMBO …, 2024 - embopress.org
The first step of successful infection by any intracellular pathogen relies on its ability to
invade its host cell membrane. However, the detailed structural and molecular …

An aminoglycoside antibiotic inhibits both lipid-induced and solution-phase fibrillation of α-synuclein in vitro

A Mahapatra, S Sarkar, SC Biswas… - Chemical …, 2019 - pubs.rsc.org
Parkinson's disease (PD), closely associated with the misfolding and aggregation of the
neuronal protein α-synuclein (A-Syn), is a neurodegenerative disorder with no cure to date …

Charge-driven interaction of antimicrobial peptide NK-2 with phospholipid membranes

S Karmakar, P Maity, A Halder - ACS omega, 2017 - ACS Publications
NK-2, derived from a cationic core region of NK-lysin, displays antimicrobial activity toward
negatively charged bacterial membranes. We have studied the interaction of NK-2 with …

Studies of Protein Phase Separation Using Leishmania Kinetoplastid Membrane Protein-11

R Roy, D Sanyal, S Roychowdhury… - The Journal of …, 2025 - ACS Publications
Despite the significant understanding of phase separation in proteins with intrinsically
disordered regions, a considerable percentage of proteins without such regions also …

A novel PEGylated block copolymer in new age therapeutics for Alzheimer's disease

S Som Chaudhury, A Sannigrahi, M Nandi… - Molecular …, 2019 - Springer
The amyloid cascade hypothesis dealing with the senile plaques is until date thought to be
one of the causative pathways leading to the pathophysiology of Alzheimer's disease (AD) …

Conformational Switch Driven Membrane Pore Formation by Mycobacterium Secretory Protein MPT63 Induces Macrophage Cell Death

A Sannigrahi, I Nandi, S Chall, JJ Jawed… - ACS chemical …, 2019 - ACS Publications
Virulent Mycobacterium tuberculosis (MTB) strains cause cell death of macrophages (Mϕ)
inside TB granuloma using a mechanism which is not well understood. Many bacterial …