Molecular biology of steroid hormone synthesis
WL Miller - Endocrine reviews, 1988 - academic.oup.com
Introduction S TEROID hormones are familiar clinically and physiologically as regulators of
physiological processes. Five groups of steroid hormones are generally recognized …
physiological processes. Five groups of steroid hormones are generally recognized …
Primary aldosteronism: changing definitions and new concepts of physiology and pathophysiology both inside and outside the kidney
M Stowasser, RD Gordon - Physiological reviews, 2016 - journals.physiology.org
In the 60 years that have passed since the discovery of the mineralocorticoid hormone
aldosterone, much has been learned about its synthesis (both adrenal and extra-adrenal) …
aldosterone, much has been learned about its synthesis (both adrenal and extra-adrenal) …
The Arabidopsis cytochrome P450 CYP707A encodes ABA 8′‐hydroxylases: key enzymes in ABA catabolism
T Kushiro, M Okamoto, K Nakabayashi… - The EMBO …, 2004 - embopress.org
The hormonal action of abscisic acid (ABA) in plants is controlled by the precise balance
between its biosynthesis and catabolism. In plants, ABA 8′‐hydroxylation is thought to play …
between its biosynthesis and catabolism. In plants, ABA 8′‐hydroxylation is thought to play …
Ecdysteroid chemistry and biochemistry
R Lafont, C Dauphin-Villemant, JT Warren, H Rees - Insect endocrinology, 2012 - Elsevier
Publisher Summary This chapter focuses on the techniques used for ecdysteroid analysis
and the biosynthesis and metabolism of these hormones. Ecdysteroids could be defined …
and the biosynthesis and metabolism of these hormones. Ecdysteroids could be defined …
11β-Hydroxyandrostenedione, the product of androstenedione metabolism in the adrenal, is metabolized in LNCaP cells by 5α-reductase yielding 11β-hydroxy-5α …
Abstract 11β-Hydroxyandrostenedione (11OHA4), which is unique to the adrenal, was first
isolated from human adrenal tissue in the fifties. It was later shown in the sixties that 11β …
isolated from human adrenal tissue in the fifties. It was later shown in the sixties that 11β …
Steroidogenic electron transport in adrenal cortex mitochondria
The flavoprotein NADPH-adrenodoxin reductase and the iron sulfur protein adrenodoxin
function as a short electron transport chain which donates electrons one-at-a-time to adrenal …
function as a short electron transport chain which donates electrons one-at-a-time to adrenal …
The influence of Aspalathus linearis (Rooibos) and dihydrochalcones on adrenal steroidogenesis: quantification of steroid intermediates and end products in H295R …
The steroid hormone output of the adrenal gland is crucial in the maintenance of hormonal
homeostasis, with hormonal imbalances being associated with numerous clinical conditions …
homeostasis, with hormonal imbalances being associated with numerous clinical conditions …
Functional zonation of the rat adrenal cortex: the development and maintenance
F Mitani - Proceedings of the Japan Academy, Series B, 2014 - jstage.jst.go.jp
The adrenal cortex of mammals consists of three concentric zones, ie, the zona glomerulosa
(zG), the zona fasciculata (zF), and the zona reticularis (zR), which secrete …
(zG), the zona fasciculata (zF), and the zona reticularis (zR), which secrete …
11β-Hydroxyandrostenedione: downstream metabolism by 11βHSD, 17βHSD and SRD5A produces novel substrates in familiar pathways
Abstract 11β-Hydroxyandrostenedione (11OHA4), a major C19 steroid produced by the
adrenal, was first reported in the 1950s. Initially the subject of numerous studies, interest …
adrenal, was first reported in the 1950s. Initially the subject of numerous studies, interest …
The CYP11B subfamily
The biosynthesis of steroid hormones is dependent on P450-catalyzed reactions. In
mammals, cholesterol is the common precursor of all steroid hormones, and its conversion …
mammals, cholesterol is the common precursor of all steroid hormones, and its conversion …