Factors affecting antimicrobial resistance in Streptococcus pneumoniae following vaccination introduction
Streptococcus pneumoniae is a major cause of pneumonia, meningitis, and septicaemia
worldwide. Pneumococcal antimicrobial resistance (AMR) has been highlighted by the WHO …
worldwide. Pneumococcal antimicrobial resistance (AMR) has been highlighted by the WHO …
Bacterial meningitis in Africa
Bacterial meningitis differs globally, and the incidence and case fatality rates vary by region,
country, pathogen, and age group; being a life-threatening disease with a high case fatality …
country, pathogen, and age group; being a life-threatening disease with a high case fatality …
The metabolic, virulence and antimicrobial resistance profiles of colonising Streptococcus pneumoniae shift after PCV13 introduction in urban Malawi
Streptococcus pneumoniae causes substantial mortality among children under 5-years-old
worldwide. Polysaccharide conjugate vaccines (PCVs) are highly effective at reducing …
worldwide. Polysaccharide conjugate vaccines (PCVs) are highly effective at reducing …
Waning of antibody levels induced by a 13-valent pneumococcal conjugate vaccine, using a 3+ 0 schedule, within the first year of life among children younger than 5 …
Summary Background Pneumococcal conjugate vaccines (PCVs) induce serotype-specific
IgG antibodies, effectively reducing vaccine-serotype carriage and invasive pneumococcal …
IgG antibodies, effectively reducing vaccine-serotype carriage and invasive pneumococcal …
Pneumococcal infections in children with sickle cell disease before and after pneumococcal conjugate vaccines
Children with sickle cell disease (SCD) are at increased risk of invasive pneumococcal
disease (IPD). Over 25 years, the Georgia Emerging Infections Program/Centers for Disease …
disease (IPD). Over 25 years, the Georgia Emerging Infections Program/Centers for Disease …
Effect of 13-valent pneumococcal conjugate vaccine on experimental carriage of Streptococcus pneumoniae serotype 6B in Blantyre, Malawi: a randomised controlled …
D Dula, B Morton, T Chikaonda, AE Chirwa… - The Lancet …, 2023 - thelancet.com
Background The effect of childhood pneumococcal conjugate vaccine implementation in
Malawi is threatened by absence of herd effect. There is persistent vaccine-type …
Malawi is threatened by absence of herd effect. There is persistent vaccine-type …
[HTML][HTML] Quality of antibody responses by adults and young children to 13-valent pneumococcal conjugate vaccination and Streptococcus pneumoniae colonisation
Childhood pneumococcal conjugate vaccine (PCV) protects against invasive pneumococcal
disease caused by vaccine-serotype (VT) Streptococcus pneumoniae by generating …
disease caused by vaccine-serotype (VT) Streptococcus pneumoniae by generating …
The Molecular Approaches and Challenges of Seroty** for Epidemiological Surveillance in the Vaccine Era
Streptococcus pneumoniae (pneumococcus) belongs to the Gram-positive cocci. This
bacterium typically colonizes the nasopharyngeal region of healthy individuals. It has a …
bacterium typically colonizes the nasopharyngeal region of healthy individuals. It has a …
Update on the evolving landscape of pneumococcal capsule types: new discoveries and way forward
SUMMARY Streptococcus pneumoniae (the “pneumococcus”) is a significant human
pathogen. The key determinant of pneumococcal fitness and virulence is its ability to …
pathogen. The key determinant of pneumococcal fitness and virulence is its ability to …
Estimating pneumococcal carriage dynamics in adults living with HIV in a mature infant pneumococcal conjugate vaccine programme in Malawi, a modelling study
J Phiri, L Sibale, L Mlongoti, N Mitole, A Kusakala… - BMC medicine, 2024 - Springer
Background Adults living with human immunodeficiency virus (ALWHIV) receiving
antiretroviral therapy (ART) exhibit higher pneumococcal carriage prevalence than adults …
antiretroviral therapy (ART) exhibit higher pneumococcal carriage prevalence than adults …