Recent advances in mass spectrometry based clinical proteomics: applications to cancer research

A Macklin, S Khan, T Kislinger - Clinical proteomics, 2020 - Springer
Cancer biomarkers have transformed current practices in the oncology clinic. Continued
discovery and validation are crucial for improving early diagnosis, risk stratification, and …

Multiomic analysis of cytokines in immuno-oncology

V Jurisic - Expert review of proteomics, 2020 - Taylor & Francis
Introduction: Cytokines are a diverse group of peptides produced by different cell types
including cancer cells and various subpopulations of immune system cells. They exert their …

Comparison of protein quantification in a complex background by DIA and TMT workflows with fixed instrument time

J Muntel, J Kirkpatrick, R Bruderer… - Journal of proteome …, 2019 - ACS Publications
Label-free quantification (LFQ) and isobaric labeling quantification (ILQ) are among the most
popular protein quantification workflows in discovery proteomics. Here, we compared the …

A multiregional proteomic survey of the postnatal human brain

BC Carlyle, RR Kitchen, JE Kanyo, EZ Voss… - Nature …, 2017 - nature.com
Detailed observations of transcriptional, translational and post-translational events in the
human brain are essential to improving our understanding of its development, function and …

The Interleukin‐1 (IL‐1) superfamily cytokines and their single nucleotide polymorphisms (SNPs)

P Behzadi, AS Sameer, S Nissar… - Journal of …, 2022 - Wiley Online Library
Interleukins (ILs)—which are important members of cytokines—consist of a vast group of
molecules, including a wide range of immune mediators that contribute to the immunological …

Chronic empagliflozin treatment reduces myocardial infarct size in nondiabetic mice through STAT-3-mediated protection on microvascular endothelial cells and …

PE Nikolaou, P Efentakis, F Abu Qourah… - Antioxidants & redox …, 2021 - liebertpub.com
Aims: Empagliflozin (EMPA) demonstrates cardioprotective effects on diabetic myocardium
but its infarct-sparing effects in normoglycemia remain unspecified. We investigated the …

Proteomics in fisheries and aquaculture: An approach for food security

MU Nissa, N Pinto, H Parkar, M Goswami, S Srivastava - Food Control, 2021 - Elsevier
Background Aquaculture is expected to continue at a faster growth rate than other major
food production sectors as there is an increasing average per capita intake of animal protein …

A comprehensive review on molecular mechanism of defective dry‐cured ham with excessive pastiness, adhesiveness, and bitterness by proteomics insights

CY Zhou, DD Pan, JX Cao… - … Reviews in Food Science …, 2021 - Wiley Online Library
Excessive bitterness, pastiness, and adhesiveness are the main organoleptic and textural
defects of dry‐cured ham, which often cause a lot of financial losses to manufacturers and …

Proteomics biomarkers for solid tumors: Current status and future prospects

I Belczacka, A Latosinska, J Metzger… - Mass spectrometry …, 2019 - Wiley Online Library
Cancer is a heterogeneous multifactorial disease, which continues to be one of the main
causes of death worldwide. Despite the extensive efforts for establishing accurate diagnostic …

Robust summarization and inference in proteome-wide label-free quantification

A Sticker, L Goeminne, L Martens… - Molecular & Cellular …, 2020 - mcponline.org
Label-Free Quantitative mass spectrometry based workflows for differential expression (DE)
analysis of proteins impose important challenges on the data analysis because of peptide …