The stimulator of interferon genes (STING) cellular signaling pathway is a promising target
for cancer immunotherapy. Activation of the intracellular STING protein triggers the …

As an essential micronutrient, manganese (Mn) participates in various physiological
processes and plays important roles in host immune system, hematopoiesis, endocrine …

Cancer immunotherapy effect can be greatly enhanced by other methods to induce
immunogenic cell death (ICD), which has profoundly affected immunotherapy as a highly …

Cancer immunotherapy holds great promise but is generally limited by insufficient induction
of anticancer immune responses. Here, a metal micellar nanovaccine is developed by the …

Adjuvant is an essential component in subunit vaccines. Many agonists of pathogen
recognition receptors have been developed as potent adjuvants to optimize the …

Dendritic cells (DCs) play a key role in the presentation of tumor antigens to initiate innate
and adaptive immune responses. While the tumor microenvironment (TME) contains a …

Immunotherapy has efficiently revolutionized the treatment of human neoplastic diseases.
However, the overall responsive rate of current immunotherapy is still unsatisfactory …

Cyclic dinucleotides (CDNs), as one type of Stimulator of Interferon Genes (STING) pathway
agonist, have shown promising results for eliciting immune responses against cancer and …

Previous studies have found that activated CD8+ T cells secrete elevated levels of interferon‐
gamma (IFN‐γ) to trigger ferroptosis in tumor cells. However, IFN‐γ‐mediated ferroptosis is …

Cancer vaccination is an effective way to prevent or cure cancers by inducing strong cellular
and humoral immunity with the aid of delivery carriers or adjuvants. Increasing new delivery …