The antiphospholipid syndrome

JS Levine, DW Branch, J Rauch - New England Journal of …, 2002 - Mass Medical Soc
The antiphospholipid syndrome is an autoimmune disorder of hypercoagulability
characterized by the presence of autoantibodies to various phospholipids or phospholipid …

Pathophysiologic implications of membrane phospholipid asymmetry in blood cells

RFA Zwaal, AJ Schroit - Blood, The Journal of the American …, 1997 - ashpublications.org
M tivities seem to work in concert to maintain a nonrandom ANY STUDIES HAVE led to the
concept that membrane phospholipid asymmetry is ubiquitous. In gen- transbilayer …

A lipid associated with the antiphospholipid syndrome regulates endosome structure and function

T Kobayashi, E Stang, KS Fang, P De Moerloose… - Nature, 1998 - nature.com
Little is known about the structure and function of membrane domains in the vacuolar
apparatus of animal cells. A unique feature of late endosomes, which are part of the pathway …

Anticardiolipin antibodies recognize beta 2-glycoprotein I structure altered by interacting with an oxygen modified solid phase surface.

E Matsuura, Y Igarashi, T Yasuda, DA Triplett… - The Journal of …, 1994 - rupress.org
Anticardiolipin antibodies (aCL) derived from the sera of individuals exhibiting the
antiphospholipid syndrome (APS) directly bind to beta 2-glycoprotein I (beta 2-GPI), which is …

Antiphospholipid antibodies affect trophoblast gonadotropin secretion and invasiveness by binding directly and through adhered β2‐glycoprotein I

N Di Simone, PL Meroni, N Del Papa… - … : Official Journal of …, 2000 - Wiley Online Library
Objective To investigate the in vitro ability of antiphospholipid antibodies (aPL) to bind
human trophoblast cells and to affect gonadotropin secretion and invasiveness. Methods …

[HTML][HTML] Autoantibodies to phospholipid-binding plasma proteins: a new view of lupus anticoagulants and other “antiphospholipid” autoantibodies

RAS Roubey - Blood, 1994 - Elsevier
LUPUS ANTICOAGULANTS, and “antiphospholipid” autoantibodies in general, are of
considerable clinical importance because of their strong association with thrombosis …

Diabetic neuropathy: pathogenesis and therapy

AI Vinik - The American journal of medicine, 1999 - Elsevier
Diabetic neuropathies are complex, heterogeneous disorders that encompass a wide range
of abnormalities affecting both peripheral and autonomic nervous systems, causing …

Crossreaction between antibodies to oxidised low-density lipoprotein and to cardiolipin in systemic lupus erythematosus

O Vaarala, K Aho, T Palosuo, G Alfthan, M Jauhiainen… - The Lancet, 1993 - Elsevier
Serum lipoproteins contain phospholipids and modified low-density lipoprotein (LDL) may
thus act as a target for antiphospholipid antibodies. Raised concentrations of IgG antibodies …

A best practice position statement on pregnancy in chronic kidney disease: the Italian Study Group on Kidney and Pregnancy

G Cabiddu, S Castellino, G Gernone, D Santoro… - Journal of …, 2016 - Springer
Pregnancy is increasingly undertaken in patients with chronic kidney disease (CKD) and,
conversely, CKD is increasingly diagnosed in pregnancy: up to 3% of pregnancies are …

Anti-cardiolipin antibodies and risk of myocardial infarction in a prospective cohort of middle-aged men

O Vaarala, M Mänttäri, V Manninen, L Tenkanen… - Circulation, 1995 - Am Heart Assoc
Background Data concerning the relation between anti-phospholipid (aPL) antibodies and
myocardial infarction in subjects without evidence of overt autoimmune disease are …