Many intracellular pathogens hijack host cell actin or its regulators for cell-to-cell spreading.
In marked contrast, apicomplexan parasites, obligate intracellular, single cell eukaryotes that …

5-methylcytosine (m5C) is an important epitranscriptomic modification involved in
messenger RNA (mRNA) stability and translation efficiency in various biological processes …

Apicomplexan parasites are the causative agents of notorious human and animal diseases
that give rise to considerable human suffering and economic losses worldwide. The most …

Cell motility is essential for protozoan and metazoan organisms and typically relies on the
dynamic turnover of actin filaments. In metazoans, monomeric actin polymerises into usually …

Apicomplexan parasites rely on actin-based gliding motility to move across the substratum,
cross biological barriers, and invade their host cells. Gliding motility depends on …

Malaria parasite cell motility is a process that is dependent on the dynamic turnover of
parasite-derived actin filaments. Despite its central role, actin's polymerization state is …

Background Scabies impairs the health of humans and animals and causes heavy
economic losses. Traditional diagnostic methods for scabies are inefficient and ineffective …

Apicomplexan parasites, such as the malaria-causing Plasmodium, utilize an actin-based
motor for motility and host cell invasion. The actin filaments of these parasites are unusually …

Cryptosporidium is a highly pathogenic water and food-borne zoonotic parasitic protozoan
that causes severe diarrhea in humans and animals. Apicomplexan parasites invade host …

Proteins of the actin-depolymerizing factor (ADF)/cofilin family have been shown to be
crucial for the motility and survival of apicomplexan parasites. However, the mechanisms by …