Atherosclerosis is the underlying cause of heart attack and stroke. Early observations that
cholesterol is a key component of arterial plaques gave rise to the cholesterol hypothesis for …

Oxidized lipids are generated from (poly) unsaturated diacyl-and alk (en) ylacyl
glycerophospholipids under conditions of oxidative stress. The great variety of reaction …

Myocardial ischemia-reperfusion (I/R) injury increases the generation of oxidized
phosphatidylcholines (OxPCs), which results in cell death. However, the mechanism by …

Atherosclerosis is a vascular disease characterized by lipid deposition and inflammation
within the arterial wall. Oxidized phospholipids (oxPLs), such as 1-palmitoyl-2-arachidonoyl …

Oxidized phospholipids, such as the products of the oxidation of 1-palmitoyl-2-arachidonoyl-
sn-glycero-3-phosphocholine by nonenzymatic radical attack, are known to be formed in a …

OBJECTIVE: Oxidation of LDL plays a key role in the development of atherosclerosis. HDL
may, in part, protect against atherosclerosis by inhibiting LDL oxidation. Overexpression of …

Aims Myocardial ischaemia followed by reperfusion (IR) causes an oxidative burst resulting
in cellular dysfunction. Little is known about the impact of oxidative stress on cardiomyocyte …

Peroxidation of membranes and lipoproteins converts “inert” phospholipids into a plethora of
oxidatively modified phospholipids (oxPL) that can act as signaling molecules. In this review …

Damage associated molecular patterns (DAMPs) are molecules released from dead/dying
cells following toxicant and/or environmental exposures that activate the immune response …

The omega-3 fatty acid, alpha linolenic acid (ALA) found in plant-derived foods induces
significant cardiovascular benefits when ingested. ALA may be cardioprotective during …