Protein data bank: a comprehensive review of 3D structure holdings and worldwide utilization by researchers, educators, and students

SK Burley, HM Berman, JM Duarte, Z Feng, JW Flatt… - Biomolecules, 2022 - mdpi.com
The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB),
funded by the United States National Science Foundation, National Institutes of Health, and …

RCSB Protein Data Bank (RCSB. org): delivery of experimentally-determined PDB structures alongside one million computed structure models of proteins from …

SK Burley, C Bhikadiya, C Bi, S Bittrich… - Nucleic acids …, 2023 - academic.oup.com
Abstract The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB
PDB), founding member of the Worldwide Protein Data Bank (wwPDB), is the US data center …

Efficient genome-editing tools to engineer the recalcitrant non-model industrial microorganism Zymomonas mobilis

G Binan, W Yalun, W **nyan, Y Yongfu, Z Peng… - Trends in …, 2024 - cell.com
Current biotechnology relies on a few well-studied model organisms, such as Escherichia
coli and Saccharomyces cerevisiae, for which abundant information and efficient toolkits are …

Targeting cancer with small-molecule pan-KRAS degraders

J Popow, W Farnaby, A Gollner, C Kofink, G Fischer… - Science, 2024 - science.org
Mutations in the Kirsten rat sarcoma viral oncogene homolog (KRAS) protein are highly
prevalent in cancer. However, small-molecule concepts that address oncogenic KRAS …

Integrating and formatting biomedical data as pre-calculated knowledge graph embeddings in the Bioteque

A Fernández-Torras, M Duran-Frigola, M Bertoni… - Nature …, 2022 - nature.com
Biomedical data is accumulating at a fast pace and integrating it into a unified framework is a
major challenge, so that multiple views of a given biological event can be considered …

Identification of different side effects between PARP inhibitors and their polypharmacological multi‐target rationale

D Sandhu, AA Antolin, AR Cox… - British journal of clinical …, 2022 - Wiley Online Library
Aims The aim of this study was to determine the differences and potential mechanistic
rationale for observed adverse drug reactions (ADRs) between four approved PARP …

Building structural models of a whole mycoplasma cell

M Maritan, L Autin, J Karr, MW Covert, AJ Olson… - Journal of molecular …, 2022 - Elsevier
Building structural models of entire cells has been a long-standing cross-discipline
challenge for the research community, as it requires an unprecedented level of integration …

Metagenomics: a path to understanding the gut microbiome

S Yen, JS Johnson - Mammalian Genome, 2021 - Springer
The gut microbiome is a major determinant of host health, yet it is only in the last 2 decades
that the advent of next-generation sequencing has enabled it to be studied at a genomic …

Bioinformatics approaches and big data analytics opportunities in improving fisheries and aquaculture

MA Rather, D Agarwal, TA Bhat, IA Khan, I Zafar… - International Journal of …, 2023 - Elsevier
Aquaculture has witnessed an excellent growth rate during the last two decades and offers
huge potential to provide nutritional as well as livelihood security. Genomic research has …

Biological control and plant growth promotion properties of Streptomyces albidoflavus St-220 isolated from Salvia miltiorrhiza rhizosphere

Y Du, T Wang, J Jiang, Y Wang, C Lv, K Sun… - Frontiers in Plant …, 2022 - frontiersin.org
Root rot disease caused by Fusarium oxysporum is a devastating disease of Salvia
miltiorrhiza and dramatically affected the production and quality of Sa. miltiorrhiza. Besides …