Magnetic resonance imaging (MRI): considerations and applications in radiotherapy treatment planning

VS Khoo, DP Dearnaley, DJ Finnigan… - Radiotherapy and …, 1997 - Elsevier
The emerging utilisation of conformal radiotherapy (RT) planning requires sophisticated
imaging modalities. Magnetic resonance imaging (MRI) has introduced several added …

In vivo dosimetry during external photon beam radiotherapy

M Essers, BJ Mijnheer - … Journal of Radiation Oncology* Biology* Physics, 1999 - Elsevier
In this critical review of the current practice of patient dose verification, we first demonstrate
that a high accuracy (about 1–2%, 1 SD) can be obtained. Accurate in vivo dosimetry is …

Dose escalation with three-dimensional conformal radiation therapy affects the outcome in prostate cancer

MJ Zelefsky, SA Leibel, PB Gaudin, GJ Kutcher… - International Journal of …, 1998 - Elsevier
Purpose: Three-dimensional conformal radiation therapy (3D-CRT) is a technique designed
to deliver prescribed radiation doses to localized tumors with high precision, while effectively …

Clinical experience with intensity modulated radiation therapy (IMRT) in prostate cancer

MJ Zelefsky, Z Fuks, L Happersett, HJ Lee… - Radiotherapy and …, 2000 - Elsevier
Purpose: To compare acute and late toxicities of high-dose radiation for prostate cancer
delivered by either conventional three-dimensional conformal radiation therapy (3D-CRT) or …

Radiation dose-response of human tumors

P Okunieff, D Morgan, A Niemierko, HD Suit - International Journal of …, 1995 - Elsevier
Purpose: The dose of radiation that locally controls human tumors treated electively or for
gross disease isy well defined. These doses can be useful in understanding the dose …

Estimation of tumor control probability model parameters from 3-D dose distributions of non-small cell lung cancer patients

MK Martel, RK Ten Haken, MB Hazuka, ML Kessler… - Lung cancer, 1999 - Elsevier
Tumor control probability (TCP) model calculations may be used in a relative manner to
evaluate and optimize three-dimensional (3-D) treatment plans. Using a mathematical …

Realization and verification of three-dimensional conformal radiotherapy with modulated fields

T Bortfeld, AL Boyer, W Schlegel, DL Kahler… - International Journal of …, 1994 - Elsevier
Purpose: We describe the experimental demonstration of the delivery of a three-dimensional
conformal radiotherapy dose distribution using in-field modulation of nine fixed-gantry fields …

Improvement in dose escalation using the process of adaptive radiotherapy combined with three-dimensional conformal or intensity-modulated beams for prostate …

AA Martinez, D Yan, D Lockman, D Brabbins… - International Journal of …, 2001 - Elsevier
Purpose: Advances in technology allow the creation of complex treatment plans with tightly
conforming doses. However, variations in positioning of the organ/patient with respect to …

Local control of carcinoma of the tonsil by radiation therapy: an analysis of patterns of fractionation in nine institutions

HR Withers, LJ Peters, JMG Taylor, JB Owen… - International Journal of …, 1995 - Elsevier
Purpose: To investigate the importance to outcome of treatment, for squamous cell
carcinomas of the tonsillar fossa, of dose per fraction, overall treatment duration, and total …

Simultaneous positron emission tomography (PET) assessment of metabolism with 18F-fluoro-2-deoxy-d-glucose (FDG), proliferation with 18F-fluoro-thymidine (FLT) …

P Vera, P Bohn, A Edet-Sanson, A Salles… - Radiotherapy and …, 2011 - Elsevier
OBJECTIVES: To investigate the changes in tumour proliferation (using FLT), metabolism
(using FDG), and hypoxia (using F-miso) during curative (chemo-) radiotherapy (RT) in …