High-risk prostate cancer—classification and therapy

AJ Chang, KA Autio, M Roach III, HI Scher - Nature reviews Clinical …, 2014 - nature.com
Approximately 15% of patients with prostate cancer are diagnosed with high-risk disease.
However, the current definitions of high-risk prostate cancer include a heterogeneous group …

Management of prostate cancer in older patients: updated recommendations of a working group of the International Society of Geriatric Oncology

JP Droz, M Aapro, L Balducci, H Boyle… - The lancet …, 2014 - thelancet.com
Summary In 2010, the International Society of Geriatric Oncology (SIOG) developed
treatment guidelines for men with prostate cancer who are older than 70 years old. In 2013 …

Accelerating histopathology workflows with generative AI-based virtually multiplexed tumour profiling

P Pati, S Karkampouna, F Bonollo… - Nature machine …, 2024 - nature.com
Understanding the spatial heterogeneity of tumours and its links to disease initiation and
progression is a cornerstone of cancer biology. Presently, histopathology workflows heavily …

Early salvage radiotherapy following radical prostatectomy

D Pfister, M Bolla, A Briganti, P Carroll, C Cozzarini… - European urology, 2014 - Elsevier
Context Depending on the pathologic tumour stage, up to 60% of prostate cancer patients
who undergo radical prostatectomy will develop biochemical relapse and require further …

The role of magnetic resonance imaging in the diagnosis and management of prostate cancer

J Thompson, N Lawrentschuk, M Frydenberg… - BJU …, 2013 - Wiley Online Library
Background The diagnosis of prostate cancer has long been plagued by the absence of an
imaging tool that reliably detects and localises significant tumours. Recent evidence …

The role of robot-assisted radical prostatectomy and pelvic lymph node dissection in the management of high-risk prostate cancer: a systematic review

B Yuh, W Artibani, A Heidenreich, S Kimm, M Menon… - European urology, 2014 - Elsevier
Context The role of robot-assisted radical prostatectomy (RARP) for men with high-risk (HR)
prostate cancer (PCa) has not been well studied. Objective To evaluate the indications for …

Long-term cancer control outcomes in patients with clinically high-risk prostate cancer treated with robot-assisted radical prostatectomy: results from a multi …

F Abdollah, A Sood, JD Sammon, L Hsu, B Beyer… - European urology, 2015 - Elsevier
Background Long-term cancer control outcomes in clinically high-risk prostate cancer (PCa)
patients treated with robot-assisted radical prostatectomy (RARP) remain unknown …

Ten-and 15-yr prostate cancer-specific mortality in patients with nonmetastatic locally advanced or aggressive intermediate prostate cancer, randomized to lifelong …

SD Fosså, F Wiklund, O Klepp, A Angelsen, A Solberg… - European urology, 2016 - Elsevier
Background In high-risk prostate cancer (PCa), no study with observation times beyond 10
yr has demonstrated survival improvement after addition of prostatic radiotherapy (RAD) to …

MRI displays the prostatic cancer anatomy and improves the bundles management before robot-assisted radical prostatectomy

R Schiavina, L Bianchi, M Borghesi… - Journal of …, 2018 - liebertpub.com
Objectives: To evaluate the impact of multiparametric magnetic0 resonance imaging
(mpMRI) to guide the nerve-sparing (NS) surgical plan in prostate cancer (PCa) patients …

Impact of age and comorbidities on long-term survival of patients with high-risk prostate cancer treated with radical prostatectomy: a multi-institutional competing-risks …

A Briganti, M Spahn, S Joniau, P Gontero, M Bianchi… - European urology, 2013 - Elsevier
BACKGROUND: Survival after surgical treatment using competing-risk analysis has been
previously examined in patients with prostate cancer (PCa). However, the combined effect of …