Long non-coding RNAs (lncRNAs) in spermatogenesis and male infertility

M Joshi, S Rajender - Reproductive Biology and Endocrinology, 2020 - Springer
Abstract Background Long non-coding RNAs (lncRNAs) have a size of more than 200 bp
and are known to regulate a host of crucial cellular processes like proliferation …

Besides pathology: long non-coding RNA in cell and tissue homeostasis

A Salviano-Silva, SC Lobo-Alves, RC Almeida… - Non-coding RNA, 2018 - mdpi.com
A significant proportion of mammalian genomes corresponds to genes that transcribe long
non-coding RNAs (lncRNAs). Throughout the last decade, the number of studies concerning …

Alterations in sperm long RNA contribute to the epigenetic inheritance of the effects of postnatal trauma

K Gapp, G van Steenwyk, PL Germain… - Molecular …, 2020 - nature.com
Psychiatric diseases have a strong heritable component known to not be restricted to DNA
sequence-based genetic inheritance alone but to also involve epigenetic factors in germ …

The Tug1 lncRNA locus is essential for male fertility

JP Lewandowski, G Dumbović, AR Watson, T Hwang… - Genome biology, 2020 - Springer
Abstract Background Several long noncoding RNAs (lncRNAs) have been shown to function
as components of molecular machines that play fundamental roles in biology. While the …

Loss-of-function in testis-specific serine/threonine protein kinase triggers male infertility in an invasive moth

Z Wei, Y Wang, K Zheng, Z Wang, R Liu… - Communications …, 2024 - nature.com
Genetic biocontrol technologies present promising and eco-friendly strategies for the
management of pest and insect-transmitted diseases. Although considerable advancements …

[HTML][HTML] Towards a multi-omics of male infertility

AO Wagner, A Turk, T Kunej - The world journal of men's health, 2023 - ncbi.nlm.nih.gov
Infertility is a common problem affecting one in six couples and in 30% of infertile couples,
the male factor is a major cause. A large number of genes are involved in spermatogenesis …

Reverse-genetics studies of lncRNAs—what we have learnt and paths forward

F Gao, Y Cai, P Kapranov, D Xu - Genome biology, 2020 - Springer
Long non-coding RNAs (lncRNAs) represent a major fraction of the transcriptome in
multicellular organisms. Although a handful of well-studied lncRNAs are broadly recognized …

Kastor and Polluks polypeptides encoded by a single gene locus cooperatively regulate VDAC and spermatogenesis

S Mise, A Matsumoto, K Shimada, T Hosaka… - Nature …, 2022 - nature.com
Although several long noncoding RNAs (lncRNAs) have recently been shown to encode
small polypeptides, those in testis remain largely uncharacterized. Here we identify two …

lncRNAs in plant and animal sexual reproduction

AA Golicz, PL Bhalla, MB Singh - Trends in plant science, 2018 - cell.com
Long noncoding RNAs (lncRNAs) are transcripts over 200 base pairs in length with no
discernible protein-coding potential. Multiple lines of evidence point to lncRNAs as master …

Expression profiles and characteristics of human lncRNA in normal and asthenozoospermia sperm

X Zhang, P Zhang, D Song, S **ong… - Biology of …, 2019 - academic.oup.com
Increasing studies have shown that specific mRNAs and miRNAs expressed in mature
sperm may be related to sperm motility. However, the expression profiles and roles of …