[HTML][HTML] Role of microbiota-derived short-chain fatty acids in cancer development and prevention

R Mirzaei, A Afaghi, S Babakhani, MR Sohrabi… - Biomedicine & …, 2021 - Elsevier
Following cancer, cells in a particular tissue can no longer respond to the factors involved in
controlling cell survival, differentiation, proliferation, and death. In recent years, it has been …

Gut microbiota-derived short-chain fatty acids regulate gastrointestinal tumor immunity: a novel therapeutic strategy?

Y Dong, K Zhang, J Wei, Y Ding, X Wang… - Frontiers in …, 2023 - frontiersin.org
Tumor immune microenvironment (TIME), a tumor-derived immune component, is proven to
be closely related to the development, metastasis, and recurrence of tumors. Gut microbiota …

Repressed Blautia-acetate immunological axis underlies breast cancer progression promoted by chronic stress

L Ye, Y Hou, W Hu, H Wang, R Yang, Q Zhang… - Nature …, 2023 - nature.com
Chronic stress is a known risk factor for breast cancer, yet the underlying mechanisms are
unclear. This study explores the potential involvement of microbial and metabolic signals in …

Modulation of the tumor microenvironment by microbiota-derived short-chain fatty acids: impact in colorectal cancer therapy

S Gomes, AC Rodrigues, V Pazienza… - International Journal of …, 2023 - mdpi.com
Finding new therapeutic approaches towards colorectal cancer (CRC) is of increased
relevance, as CRC is one of the most common cancers worldwide. CRC standard therapy …

The roles of microbial products in the development of colorectal cancer: a review

Y Fang, C Yan, Q Zhao, J Xu, Z Liu, J Gao, H Zhu… - …, 2021 - Taylor & Francis
ABSTRACT A large number of microbes exist in the gut and they have the ability to process
and utilize ingested food. It has been reported that their products are involved in colorectal …

BODIPY-decorated nanoscale covalent organic frameworks for photodynamic therapy

Q Guan, DD Fu, YA Li, XM Kong, ZY Wei, WY Li… - IScience, 2019 - cell.com
Covalent organic frameworks (COFs), an emerging class of organic porous materials, have
attracted intense attention due to their versatile applications. However, the deliberate …

Acetate revisited: a key biomolecule at the nexus of metabolism, epigenetics, and oncogenesis–part 2: acetate and ACSS2 in health and disease

JR Moffett, N Puthillathu, R Vengilote… - Frontiers in …, 2020 - frontiersin.org
Acetate, the shortest chain fatty acid, has been implicated in providing health benefits
whether it is derived from the diet or is generated from microbial fermentation of fiber in the …

[HTML][HTML] Gut microbiome-metabolites axis: A friend or foe to colorectal cancer progression

H Wu, W Ma, Y Wang, Y Wang, X Sun… - Biomedicine & …, 2024 - Elsevier
An expanding corpus of research robustly substantiates the complex interrelation between
gut microbiota and the onset, progression, and metastasis of colorectal cancer …

The role of diet related short-chain fatty acids in colorectal cancer metabolism and survival: prevention and therapeutic implications

SD Gomes, CS Oliveira, J Azevedo-Silva… - Current medicinal …, 2020 - benthamdirect.com
Colorectal Cancer (CRC) is a major cause of cancer-related death worldwide. CRC
increased risk has been associated with alterations in the intestinal microbiota, with …

Glucagon-like peptide 1 protects pancreatic β-cells from death by increasing autophagic flux and restoring lysosomal function

FP Zummo, KS Cullen, M Honkanen-Scott… - Diabetes, 2017 - diabetesjournals.org
Studies in animal models of type 2 diabetes have shown that glucagon-like peptide 1 (GLP-
1) receptor agonists prevent β-cell loss. Whether GLP-1 mediates β-cell survival via the key …