The transforming growth factor β (TGF-β) family of growth factors control the development
and homeostasis of most tissues in metazoan organisms. Work over the past few years has …

Progressive fibrosis in the kidney, liver, lung, heart, bone marrow, and skin is both a major
cause of suffering and death and an important contributor to the cost of health care. All of this …

Simultaneous recordings were made from large ensembles of hippocampal" place cells" in
three rats during spatial behavioral tasks and in slow-wave sleep preceding and following …

Transforming growth factor-β (TGF-β) signals by contacting two distantly related transmem-
brane serine/threonine kinases called receptors I and II. The role of these molecules in …

In the last 10 years, a large family of secreted signaling molecules has been discovered that
appear to mediate many key events in normal growth and development. The family is known …

The secreted polypeptide transforming growth factor-beta (TGF-beta) exerts its multiple
activities through type I and II cell surface receptors. In epithelial cells, activation of the TGF …

Interstitial fibrosis, associated with extensive accumulation of extracellular matrix
constituents in the cortical interstitium, is directly correlated to progression of renal disease …

Transforming growth factors (TGFs) were discovered as activities that were secreted by
cancer cells, and later by normal cells, and had the ability to phenotypically and reversibly …

Members of the TGF-β superfamily, which includes TGF-βs, growth differentiation factors,
bone morphogenetic proteins, activins, inhibins, and glial cell line-derived neurotrophic …

The transforming growth factor-β (TGF-β) superfamily of receptors comprises two groups of
transmembrane serine-threonine kinase receptors, so called type I, and type II receptors …