While Nature harnesses RNA and DNA to store, read and write genetic information, the
inherent programmability, synthetic accessibility and wide functionality of these nucleic acids …

Nucleic acid aptamers are ssDNA or ssRNA fragments that specifically recognize targets.
However, the pharmacodynamic properties of natural aptamers consisting of 4 naturally …

Little is known about the biological roles of glycosylated RNAs (glycoRNAs), a recently
discovered class of glycosylated molecules, because of a lack of visualization methods. We …

Abstract Development of plasmonic biosensors combining reliability and ease of use is still a
challenge. Gold nanoparticle arrays made by block copolymer micelle nanolithography …

In the past three decades, in vitro systematic evolution of ligands by exponential enrichment
(SELEX) has yielded many aptamers for translational applications in both research and …

We report a series of 2′-deoxyribonucleoside triphosphates bearing dicarba-nido-
undecaborate ([C2B9H11] 1–),[3, 3′-iron-bis (1, 2-dicarbollide)]−(FESAN,[Fe (C2B9H11) 2] …

In vitro evolution strategies have been used for> 30 years to generate nucleic acid aptamers
against therapeutic targets of interest, including disease-associated proteins. However, this …

Multivalent display of SARS-CoV-2 RBDs (receptor-binding domains, prime proteins for viral
infection and as vaccine immunogens) affects infectivity and as immunogens on a virus-like …

Beyond the natural nucleic acids DNA and RNA, nucleic acid chemistry has unlocked a
whole universe of modifications to their canonical chemical structure, which can in various …

Malaria is an infectious disease caused by parasitic protozoans from the genus
Plasmodium, with the species P. falciparum causing the highest number of deaths …