Gut microbiota in human metabolic health and disease

Y Fan, O Pedersen - Nature Reviews Microbiology, 2021 - nature.com
Observational findings achieved during the past two decades suggest that the intestinal
microbiota may contribute to the metabolic health of the human host and, when aberrant, to …

The microbiota-gut-brain axis

JF Cryan, KJ O'Riordan, CSM Cowan… - Physiological …, 2019 - journals.physiology.org
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …

Large-scale association analyses identify host factors influencing human gut microbiome composition

A Kurilshikov, C Medina-Gomez, R Bacigalupe… - Nature …, 2021 - nature.com
To study the effect of host genetics on gut microbiome composition, the MiBioGen
consortium curated and analyzed genome-wide genotypes and 16S fecal microbiome data …

[HTML][HTML] The role of short-chain fatty acids from gut microbiota in gut-brain communication

YP Silva, A Bernardi, RL Frozza - Frontiers in endocrinology, 2020 - frontiersin.org
A substantial body of evidence supports that the gut microbiota plays a pivotal role in the
regulation of metabolic, endocrine and immune functions. In recent years, there has been …

Programmable probiotics modulate inflammation and gut microbiota for inflammatory bowel disease treatment after effective oral delivery

J Zhou, M Li, Q Chen, X Li, L Chen, Z Dong… - Nature …, 2022 - nature.com
Reactive oxygen species (ROS) play vital roles in intestinal inflammation. Therefore,
eliminating ROS in the inflammatory site by antioxidant enzymes such as catalase and …

Gut microbiota and short chain fatty acids: implications in glucose homeostasis

P Portincasa, L Bonfrate, M Vacca… - International journal of …, 2022 - mdpi.com
Gut microbiota encompasses a wide variety of commensal microorganisms consisting of
trillions of bacteria, fungi, and viruses. This microbial population coexists in symbiosis with …

Association between gut microbiota and preeclampsia-eclampsia: a two-sample Mendelian randomization study

P Li, H Wang, L Guo, X Gou, G Chen, D Lin, D Fan… - BMC medicine, 2022 - Springer
Background Several recent observational studies have reported that gut microbiota
composition is associated with preeclampsia. However, the causal effect of gut microbiota …

Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets

JH Zhao, D Stacey, N Eriksson… - Nature …, 2023 - nature.com
Circulating proteins have important functions in inflammation and a broad range of diseases.
To identify genetic influences on inflammation-related proteins, we conducted a genome …

[HTML][HTML] Role of gut microbiota in type 2 diabetes pathophysiology

M Gurung, Z Li, H You, R Rodrigues, DB Jump… - …, 2020 - thelancet.com
A substantial body of literature has provided evidence for the role of gut microbiota in
metabolic diseases including type 2 diabetes. However, reports vary regarding the …

Probiotics and prebiotics in intestinal health and disease: from biology to the clinic

ME Sanders, DJ Merenstein, G Reid… - Nature reviews …, 2019 - nature.com
Probiotics and prebiotics are microbiota-management tools for improving host health. They
target gastrointestinal effects via the gut, although direct application to other sites such as …