Risk factors for migraine disease progression: a narrative review for a patient-centered approach

RB Lipton, DC Buse, SJ Nahas, GE Tietjen… - Journal of …, 2023‏ - Springer
Background In individuals with migraine, attacks may increase in frequency, severity, or
both. Preventing migraine progression has emerged as a treatment goal in headache …

Management of chronic migraine

A Hovaguimian, J Roth - Bmj, 2022‏ - bmj.com
Chronic migraine is a neurologic disorder associated with considerable disability, lost
productivity, and a profound economic burden worldwide. The past five years have seen a …

The American Headache Society Consensus Statement: Update on integrating new migraine treatments into clinical practice

J Ailani, RC Burch, MS Robbins… - … : The Journal of …, 2021‏ - Wiley Online Library
Objective To incorporate recent research findings, expert consensus, and patient
perspectives into updated guidance on the use of new acute and preventive treatments for …

Galcanezumab in chronic migraine: the randomized, double-blind, placebo-controlled REGAIN study

HC Detke, PJ Goadsby, S Wang, DI Friedman… - Neurology, 2018‏ - neurology.org
Objective To evaluate the efficacy and safety of galcanezumab, a humanized monoclonal
antibody that selectively binds to calcitonin gene-related peptide, in the preventive treatment …

Safety and efficacy of galcanezumab in patients for whom previous migraine preventive medication from two to four categories had failed (CONQUER): a multicentre …

WM Mulleners, BK Kim, MJA Láinez… - The Lancet …, 2020‏ - thelancet.com
Background Many patients who require migraine preventive treatment have not been able to
tolerate or have not responded to multiple previous preventive medications. We aimed to …

ARISE: a phase 3 randomized trial of erenumab for episodic migraine

DW Dodick, M Ashina, JL Brandes, D Kudrow… - …, 2018‏ - journals.sagepub.com
Background Calcitonin gene-related peptide plays an important role in migraine
pathophysiology. Erenumab, a human monoclonal antibody that inhibits the calcitonin gene …

The American Headache Society position statement on integrating new migraine treatments into clinical practice

American Headache Society - … : The Journal of Head and Face …, 2019‏ - Wiley Online Library
Objective To provide healthcare professionals with updated guidance in the use of novel
preventive and acute treatments for migraine in adults. Background The principles of …

Guidelines of the International Headache Society for controlled trials of preventive treatment of chronic migraine in adults

C Tassorelli, HC Diener, DW Dodick… - …, 2018‏ - journals.sagepub.com
Background Quality clinical trials form an essential part of the evidence base for the
treatment of headache disorders. In 1991, the International Headache Society Clinical Trials …

Long‐term efficacy and safety of erenumab in migraine prevention: results from a 5‐year, open‐label treatment phase of a randomized clinical trial

M Ashina, PJ Goadsby, U Reuter… - European journal of …, 2021‏ - Wiley Online Library
Background and purpose Although erenumab has demonstrated significant reduction in
migraine frequency and improved quality of life in studies lasting 3 to 12 months, little is …

Erenumab in chronic migraine with medication overuse: subgroup analysis of a randomized trial

SJ Tepper, HC Diener, M Ashina, JL Brandes… - Neurology, 2019‏ - neurology.org
Objective To determine the effect of erenumab, a human anti-calcitonin gene-related peptide
receptor monoclonal antibody, in patients with chronic migraine and medication overuse …