Ursolic and oleanolic acids: Plant metabolites with neuroprotective potential

E Gudoityte, O Arandarcikaite, I Mazeikiene… - International Journal of …, 2021 - mdpi.com
Ursolic and oleanolic acids are secondary plant metabolites that are known to be involved in
the plant defence system against water loss and pathogens. Nowadays these triterpenoids …

Targeting the lung tumor microenvironment by phytochemicals and their nanoformulations

SO Rab, FMA Altalbawy, M Chandra, IA Ariffin… - … -Research and Practice, 2024 - Elsevier
Lung malignancies are among the most prevalent and foremost causes of tumor-related
deaths. Despite significant advancements in the understanding and management of lung …

A review on the phytochemical and pharmacological properties of Hyptis suaveolens (L.) Poit

P Mishra, S Sohrab, SK Mishra - Future journal of pharmaceutical …, 2021 - Springer
Background Plants are the repository of variable number of valuable secondary metabolites
that bears pharmacognostic and pharmacological implications having potentiality to emerge …

[HTML][HTML] New insights into the anticancer therapeutic potential of maytansine and its derivatives

S Zafar, M Armaghan, K Khan, N Hassan… - Biomedicine & …, 2023 - Elsevier
Maytansine is a pharmacologically active 19-membered ansamacrolide derived from
various medicinal plants and microorganisms. Among the most studied pharmacological …

Ursolic acid: A natural modulator of signaling networks in different cancers

S Zafar, K Khan, A Hafeez, M Irfan, M Armaghan… - Cancer Cell …, 2022 - Springer
Incidence rate of cancer is estimated to increase by 40% in 2030. Furthermore, the
development of resistance against currently available treatment strategies has contributed to …

Ursolic acid analogs as potential therapeutics for cancer

SS Panda, M Thangaraju, BL Lokeshwar - Molecules, 2022 - mdpi.com
Ursolic acid (UA) is a pentacyclic triterpene isolated from a large variety of vegetables, fruits
and many traditional medicinal plants. It is a structural isomer of Oleanolic Acid. The …

Natural products: Potential therapeutic agents to prevent skeletal muscle atrophy

A Yadav, SS Yadav, S Singh, R Dabur - European Journal of …, 2022 - Elsevier
The skeletal muscle (SkM) is the largest organ, which plays a vital role in controlling
musculature, locomotion, body heat regulation, physical strength, and metabolism of the …

Nanoformulations of ursolic acid: a modern natural anticancer molecule

L Wang, Q Yin, C Liu, Y Tang, C Sun… - Frontiers in …, 2021 - frontiersin.org
Background: Ursolic acid (UA) is a natural pentacyclic triterpene derived from fruit, herb, and
other plants. UA can act on molecular targets of various signaling pathways, inhibit the …

[HTML][HTML] Phytochemical based nanomedicine: a panacea for cancer treatment, present status and future prospective

P Mohapatra, P Singh, D Singh, S Sahoo, SK Sahoo - OpenNano, 2022 - Elsevier
Cancer is one of the leading causes of mortality worldwide. Currently available anticancer
therapeutic strategies are not able to improve the survival rate of patients over the past few …

Pentacyclic triterpenoids with nitrogen-containing heterocyclic moiety, privileged hybrids in anticancer drug discovery

V Khwaza, S Mlala, OO Oyedeji, BA Aderibigbe - Molecules, 2021 - mdpi.com
Pentacyclic triterpenoids are well-known phytochemicals with various biological activities
commonly found in plants as secondary metabolites. The wide range of biological activities …