Acute respiratory distress syndrome in adults: diagnosis, outcomes, long-term sequelae, and management

EA Gorman, CM O'Kane, DF McAuley - The Lancet, 2022 - thelancet.com
Acute respiratory distress syndrome (ARDS) is characterised by acute hypoxaemic
respiratory failure with bilateral infiltrates on chest imaging, which is not fully explained by …

How to ventilate obese patients in the ICU

A De Jong, H Wrigge, G Hedenstierna, L Gattinoni… - Intensive care …, 2020 - Springer
Obesity is an important risk factor for major complications, morbidity and mortality related to
intubation procedures and ventilation in the intensive care unit (ICU). The fall in functional …

Ventilatory variables and mechanical power in patients with acute respiratory distress syndrome

ELV Costa, AS Slutsky, LJ Brochard… - American journal of …, 2021 - atsjournals.org
Rationale: Mortality in acute respiratory distress syndrome (ARDS) has decreased after the
adoption of lung-protective strategies. Lower Vt, lower driving pressure (ΔP), lower …

Effect of Lowering Vt on Mortality in Acute Respiratory Distress Syndrome Varies with Respiratory System Elastance

EC Goligher, ELV Costa, CJ Yarnell… - American journal of …, 2021 - atsjournals.org
Rationale: If the risk of ventilator-induced lung injury in acute respiratory distress syndrome
(ARDS) is causally determined by driving pressure rather than by Vt, then the effect of …

Bedside calculation of mechanical power during volume-and pressure-controlled mechanical ventilation

D Chiumello, M Gotti, M Guanziroli, P Formenti… - Critical care, 2020 - Springer
Background Mechanical power (MP) is the energy delivered to the respiratory system over
time during mechanical ventilation. Our aim was to compare the currently available methods …

Mechanical power during general anesthesia and postoperative respiratory failure: a multicenter retrospective cohort study

P Santer, LJ Wachtendorf, A Suleiman… - …, 2022 - ingentaconnect.com
Background: Mechanical power during ventilation estimates the energy delivered to the
respiratory system through integrating inspiratory pressures, tidal volume, and respiratory …

Effect of mechanical power on intensive care mortality in ARDS patients

S Coppola, A Caccioppola, S Froio, P Formenti… - Critical Care, 2020 - Springer
Background In ARDS patients, mechanical ventilation should minimize ventilator-induced
lung injury. The mechanical power which is the energy per unit time released to the …

Mechanical power at a glance: a simple surrogate for volume-controlled ventilation

L Giosa, M Busana, I Pasticci, M Bonifazi… - Intensive care medicine …, 2019 - Springer
Background Mechanical power is a summary variable including all the components which
can possibly cause VILI (pressures, volume, flow, respiratory rate). Since the complexity of …

High risk of patient self-inflicted lung injury in COVID-19 with frequently encountered spontaneous breathing patterns: a computational modelling study

L Weaver, A Das, S Saffaran, N Yehya, TE Scott… - Annals of intensive …, 2021 - Springer
Background There is on-going controversy regarding the potential for increased respiratory
effort to generate patient self-inflicted lung injury (P-SILI) in spontaneously breathing …

Effect of mechanical power on mortality in invasively ventilated ICU patients without the acute respiratory distress syndrome: An analysis of three randomised clinical …

DMP Van Meenen, AG Algera… - European Journal of …, 2023 - journals.lww.com
BACKGROUND The mechanical power of ventilation (MP) has an association with outcome
in invasively ventilated patients with the acute respiratory distress syndrome (ARDS) …