Molecular changes in malignant tissue can lead to an increase in the expression levels of
various proteins or receptors that can be used to target the disease. In oncology, diagnostic …

The increased use of copper radioisotopes in radiopharmaceutical applications has created
a need for bifunctional chelators (BFCs) that form stable radiocopper complexes and allow …

Cyclams are 14-membered tetraamine macrocycles which bind strongly to a wide range of
metal ions. Medical interest has centred on clinical trials of a bicyclam for the treatment of …

Molecular imaging has evolved over the past several years into an important tool for
diagnosing, understanding, and monitoring disease. Molecular imaging has distinguished …

An understanding of the metabolic fate of radiometal-labeled peptides is important due to
their application in the areas of diagnostic imaging and targeted radiotherapy …

Molecular imaging is an important scientific discipline that plays a major role in clinical
medicine and pharmaceutical development. While several imaging modalities including X …

High radiolabeling efficiency, preferably to high specific activity, and good stability of the
radioimmunoconjugate are essential features for a successful immunoconjugate for imaging …

Over the last twenty-five years 1, 4, 7, 10-tetraazacyclododecane-1, 4, 7, 10-tetraacetic acid
(DOTA) has made a significant impact on the field of diagnostic imaging. DOTA is not the …

A novel nanoparticle-based dual-modality positron emission tomograph/magnetic
resonance imaging (PET/MRI) contrast agent was developed. The probe consisted of a …