Osteoarthritis: pathogenic signaling pathways and therapeutic targets

Q Yao, X Wu, C Tao, W Gong, M Chen, M Qu… - Signal transduction and …, 2023 - nature.com
Osteoarthritis (OA) is a chronic degenerative joint disorder that leads to disability and affects
more than 500 million population worldwide. OA was believed to be caused by the wearing …

[HTML][HTML] OARSI guidelines for the non-surgical management of knee, hip, and polyarticular osteoarthritis

RR Bannuru, MC Osani, EE Vaysbrot, NK Arden… - Osteoarthritis and …, 2019 - Elsevier
Objective To update and expand upon prior Osteoarthritis Research Society International
(OARSI) guidelines by develo** patient-focused treatment recommendations for …

CDC guideline for prescribing opioids for chronic pain—United States, 2016

D Dowell, TM Haegerich, R Chou - Jama, 2016 - jamanetwork.com
Importance Primary care clinicians find managing chronic pain challenging. Evidence of
long-term efficacy of opioids for chronic pain is limited. Opioid use is associated with serious …

Osteoarthritis: pathology, diagnosis, and treatment options

B Abramoff, FE Caldera - Medical Clinics, 2020 - medical.theclinics.com
Osteoarthritis (OA) is endemic throughout the world. An estimated 30.8 million adults in the
United States and 300 million individuals worldwide are living with OA. 1, 2 It is the leading …

[HTML][HTML] OARSI guidelines for the non-surgical management of knee osteoarthritis

TE McAlindon, RR Bannuru, MC Sullivan… - Osteoarthritis and …, 2014 - Elsevier
Objective To develop concise, up-to-date, patient-focused, evidence-based, expert
consensus guidelines for the management of knee osteoarthritis (OA), intended to inform …

The burden of disease in older people and implications for health policy and practice

MJ Prince, F Wu, Y Guo, LMG Robledo, M O'Donnell… - The lancet, 2015 - thelancet.com
Summary 23% of the total global burden of disease is attributable to disorders in people
aged 60 years and older. Although the proportion of the burden arising from older people (≥ …

Non-surgical management of knee osteoarthritis: comparison of ESCEO and OARSI 2019 guidelines

NK Arden, TA Perry, RR Bannuru, O Bruyère… - Nature Reviews …, 2021 - nature.com
Knee osteoarthritis (OA) is a heterogeneous disease associated with substantial effects on
quality of life, and its clinical management is difficult. Among the several available guidelines …

[PDF][PDF] American College of Rheumatology 2012 recommendations for the use of nonpharmacologic and pharmacologic therapies in osteoarthritis of the hand, hip …

MC Hochberg, RD Altman, KT April… - Arthritis care & …, 2012 - Wiley Online Library
Abstract Objective To update the American College of Rheumatology (ACR) 2000
recommendations for hip and knee osteoarthritis (OA) and develop new recommendations …

Osteoarthritis: an update with relevance for clinical practice

JWJ Bijlsma, F Berenbaum, FPJG Lafeber - The Lancet, 2011 - thelancet.com
Osteoarthritis is thought to be the most prevalent chronic joint disease. The incidence of
osteoarthritis is rising because of the ageing population and the epidemic of obesity. Pain …

American Association of Clinical Endocrinologists and American College of Endocrinology comprehensive clinical practice guidelines for medical care of patients with …

WT Garvey, JI Mechanick, EM Brett, AJ Garber… - Endocrine Practice, 2016 - Elsevier
Objective Development of these guidelines is mandated by the American Association of
Clinical Endocrinologists (AACE) Board of Directors and the American College of …