Digital health technologies have been in use for many years in a wide spectrum of
healthcare scenarios. This narrative review outlines the current use and the future strategies …

Chronic kidney disease (CKD) is a common complex condition associated with high
morbidity and mortality. Polygenic prediction could enhance CKD screening and prevention; …

Glaring health disparities have reinvigorated debate about the relevance of race to health,
including how race should and should not be used as a variable in research and …

Identifying causal factors for Mendelian and common diseases is an ongoing challenge in
medical genetics. Population bottleneck events, such as those that occurred in the history of …

Background Exome sequencing in hundreds of thousands of persons may enable the
identification of rare protein-coding genetic variants associated with protection from human …

Polygenic scores (PGS) have emerged as the tool of choice for genomic prediction in a wide
range of fields. We show that PGS performance varies broadly across contexts and …

Asian populations are under-represented in human genomics research. Here, we
characterize clinically significant genetic variation in 9051 genomes representing East …

Precision public health (PPH) considers the interplay between genetics, lifestyle and the
environment to improve disease prevention, diagnosis and treatment on a population level …