An overview of duplicated gene detection methods: Why the duplication mechanism has to be accounted for in their choice

T Lallemand, M Leduc, C Landès, C Rizzon, E Lerat - Genes, 2020 - mdpi.com
Gene duplication is an important evolutionary mechanism allowing to provide new genetic
material and thus opportunities to acquire new gene functions for an organism, with major …

Effects of maternal exposure to social stress during pregnancy: consequences for mother and offspring

PJ Brunton - Reproduction, 2013 - rep.bioscientifica.com
Gonadotropins and their receptors' genes carry several single-nucleotide polymorphisms
resulting in endocrine genotypes modulating reproductive parameters, diseases, and …

The complete sequence and comparative analysis of ape sex chromosomes

KD Makova, BD Pickett, RS Harris, GA Hartley… - Nature, 2024 - nature.com
Apes possess two sex chromosomes—the male-specific Y chromosome and the X
chromosome, which is present in both males and females. The Y chromosome is crucial for …

Genetics on the Fly: A Primer on the Drosophila Model System

KG Hales, CA Korey, AM Larracuente, DM Roberts - Genetics, 2015 - academic.oup.com
Fruit flies of the genus Drosophila have been an attractive and effective genetic model
organism since Thomas Hunt Morgan and colleagues made seminal discoveries with them …

A benchmark of gene expression tissue-specificity metrics

N Kryuchkova-Mostacci… - Briefings in …, 2017 - academic.oup.com
One of the major properties of genes is their expression pattern. Notably, genes are often
classified as tissue specific or housekee**. This property is of interest to molecular …

Coregulation of tandem duplicate genes slows evolution of subfunctionalization in mammals

X Lan, JK Pritchard - Science, 2016 - science.org
Gene duplication is a fundamental process in genome evolution. However, most young
duplicates are degraded by loss-of-function mutations, and the factors that allow some …

A bacterial-like Pictet–Spenglerase drives the evolution of fungi to produce β-carboline glycosides together with separate genes

XL Li, Y Sun, Y Yin, S Zhan… - Proceedings of the …, 2023 - National Acad Sciences
Diverse β-carboline (βC) alkaloids are produced by microbes, plants, and animals with
myriad bioactivities and drug potentials. However, the biosynthetic mechanism of βCs …

Sex differences in disease genetics: evidence, evolution, and detection

WP Gilks, JK Abbott, EH Morrow - Trends in Genetics, 2014 - cell.com
Understanding the genetic architecture of disease is an enormous challenge, and should be
guided by evolutionary principles. Recent studies in evolutionary genetics show that sexual …

Molecular evolution across mouse spermatogenesis

EEK Kopania, EL Larson, C Callahan… - Molecular Biology …, 2022 - academic.oup.com
Genes involved in spermatogenesis tend to evolve rapidly, but we lack a clear
understanding of how protein sequences and patterns of gene expression evolve across this …

Genetics of schizophrenia: historical insights and prevailing evidence

J Van de Leemput, JL Hess, SJ Glatt, MT Tsuang - Advances in genetics, 2016 - Elsevier
Abstract Schizophrenia's (SZ's) heritability and familial transmission have been known for
several decades; however, despite the clear evidence for a genetic component, it has been …