Aging of cerebral white matter

H Liu, Y Yang, Y **a, W Zhu, RK Leak, Z Wei… - Ageing research …, 2017 - Elsevier
White matter (WM) occupies a large volume of the human cerebrum and is mainly composed
of myelinated axons and myelin-producing glial cells. The myelinated axons within WM are …

Neuroimaging of Parkinson's disease: Expanding views

CP Weingarten, MH Sundman, P Hickey… - … & Biobehavioral Reviews, 2015 - Elsevier
Advances in molecular and structural and functional neuroimaging are rapidly expanding
the complexity of neurobiological understanding of Parkinson's disease (PD). This review …

Baseline and longitudinal grey matter changes in newly diagnosed Parkinson's disease: ICICLE-PD study

E Mak, L Su, GB Williams, MJ Firbank, RA Lawson… - Brain, 2015 - academic.oup.com
Mild cognitive impairment in Parkinson's disease is associated with progression to dementia
(Parkinson's disease dementia) in a majority of patients. Determining structural imaging …

Parkinson's disease and multiple system atrophy patient iPSC-derived oligodendrocytes exhibit alpha-synuclein–induced changes in maturation and immune reactive …

C Azevedo, G Teku, Y Pomeshchik… - Proceedings of the …, 2022 - National Acad Sciences
Limited evidence has shed light on how aSYN proteins affect the oligodendrocyte
phenotype and pathogenesis in synucleinopathies that include Parkinson's disease (PD) …

Apathy and impulsivity in frontotemporal lobar degeneration syndromes

CJ Lansdall, ITS Coyle-Gilchrist, PS Jones… - Brain, 2017 - academic.oup.com
Apathy and impulsivity are common and disabling consequences of frontotemporal lobar
degeneration. They cause substantial carer distress, but their aetiology remains elusive …

Mild cognitive impairment in Parkinson's disease is associated with a distributed pattern of brain white matter damage

F Agosta, E Canu, E Stefanova, L Sarro… - Human brain …, 2014 - Wiley Online Library
This study assesses the patterns of gray matter (GM) and white matter (WM) damage in
patients with Parkinson's disease and mild cognitive impairment (PD‐MCI) compared with …

White matter microstructure deteriorates across cognitive stages in Parkinson disease

TR Melzer, R Watts, MR MacAskill, TL Pitcher… - Neurology, 2013 - AAN Enterprises
Objectives: To characterize different stages of Parkinson disease (PD)-related cognitive
decline using diffusion tensor imaging (DTI) and investigate potential relationships between …

[HTML][HTML] Vestibular insights into cognition and psychiatry

C Gurvich, JJ Maller, B Lithgow, S Haghgooie… - Brain research, 2013 - Elsevier
The vestibular system has traditionally been thought of as a balance apparatus; however,
accumulating research suggests an association between vestibular function and psychiatric …

Diffusion tensor imaging in Parkinson's disease and parkinsonian syndrome: a systematic review

Y Zhang, MA Burock - Frontiers in neurology, 2020 - frontiersin.org
Diffusion tensor imaging (DTI) allows measuring fractional anisotropy and similar
microstructural indices of the brain white matter. Lower than normal fractional anisotropy as …

The DIRECT consortium and the REST-meta-MDD project: towards neuroimaging biomarkers of major depressive disorder

X Chen, B Lu, HX Li, XY Li, YW Wang… - …, 2022 - academic.oup.com
Despite a growing neuroimaging literature on the pathophysiology of major depressive
disorder (MDD), reproducible findings are lacking, probably reflecting mostly small sample …