This chapter comprehensively explores the pivotal role of artificial intelligence (AI) in drug
discovery and development, encapsulating its potentials, methodologies, real-world …

Drug evaluation has always been an important area of research in the pharmaceutical
industry. However, animal welfare protection and other shortcomings of traditional drug …

Artificial intelligence (AI) and machine learning (ML) represent significant advancements in
computing, building on technologies that humanity has developed over millions of years …

Organ on Chip platforms hold significant promise as alternatives to animal models or
traditional cell cultures, both of which poorly recapitulate human pathophysiology and …

In vitro models of liver (patho) physiology, new technologies, and experimental approaches
are progressing rapidly. Based on cell lines, induced pluripotent stem cells or primary cells …

The interplay between mechanical stimuli and cellular mechanobiology orchestrates the
physiology of tissues and organs in a dynamic balance characterized by constant …

Microfluidic is a technology that allows the precise control of fluid in a micro-channel. With its
advantages of high throughput and low cost, microfluidic technology has achieved good …

Abstract Organ-on-chip (OoC) technology has led to in vitro models with many new
possibilities compared to conventional in vitro and in vivo models. In this review, the …

Introduction Pharmacokinetic parameters assessment is a critical aspect of drug discovery
and development, yet challenges persist due to limited training data. Despite advancements …

Metabolic diseases have been a major public health issue and a clinical challenge
worldwide. Dysfunction of metabolic homeostasis is linked to the onset of various diseases …