The flaviviruses are small single-stranded RNA viruses that are typically transmitted by
mosquito or tick vectors. These “arboviruses” are found around the world and account for a …

The tick-borne pathogen Powassan virus is a rare cause of encephalitis in North America
and the Russian Far East. The number of documented cases described since the discovery …

To generate the most diverse phylogenetic dataset for the flaviviruses to date, we
determined the genomic sequences and phylogenetic relationships of 14 flaviviruses, of …

In viral disease research, few diseases can compete with yellow fever for the volume of
literature, historical significance, richness of the topics and the amount of strong interest …

Flavivirids (family Flaviviridae) are a group of positive-strand ribonucleic acid (RNA) viruses
that pose serious risks to human and animal health on a global scale. Here, we use flavivirid …

Most described flaviviruses (family Flaviviridae) are disease-causing pathogens of
vertebrates maintained in zoonotic cycles between mosquitoes or ticks and vertebrate hosts …

Background Powassan virus (POWV), a flavivirus discovered in 1958, causes sporadic but
severe cases of encephalitis in humans. Since 2007, the number of human Powassan cases …

The RNA-dependent RNA polymerases (RdRPs) encoded by RNA viruses represent a
unique class of nucleic acid polymerases. RdRPs are essential in virus life cycle due to their …

As viral genomic imprints in host genomes, endogenous viral elements (EVEs) shed light on
the deep evolutionary history of viruses, ancestral host ranges, and ancient viral–host …

The genus Flavivirus comprises approximately 73 viruses, which share several common
aspects, such as dimension, structure, nucleic acid properties, and shape in electronic …