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On the gain of entrainment in a class of weakly contractive bilinear control systems
We consider a class of bilinear weakly contractive systems that entrain to periodic
excitations. Entrainment is important in many natural and artificial processes. For example …
excitations. Entrainment is important in many natural and artificial processes. For example …
On the gain of entrainment in the n-dimensional ribosome flow model
The ribosome flow model (RFM) is a phenomenological model for the flow of particles along
a one-dimensional chain of n sites. It has been extensively used to study ribosome flow …
a one-dimensional chain of n sites. It has been extensively used to study ribosome flow …
Signal differentiation with genetic networks
Biological counterparts of differential operators are not only likely to exist in natural systems
but also desirable to realize as modules in synthetic biology. Therefore, we present a …
but also desirable to realize as modules in synthetic biology. Therefore, we present a …
Analysis of primitive genetic interactions for the design of a genetic signal differentiator
We study the dynamic and static input–output behavior of several primitive genetic
interactions and their effect on the performance of a genetic signal differentiator. In a …
interactions and their effect on the performance of a genetic signal differentiator. In a …
Optimal experiment design and leveraging competition for shared resources in cell-free extracts
The fact that genes compete for shared cellular resources poses a fundamental challenge
when identifying parameters of genetic parts. A recently developed model of gene …
when identifying parameters of genetic parts. A recently developed model of gene …
On the gain of entrainment in a class of weakly contractive bilinear control systems with applications to the master equation and the ribosome flow model
We consider a class of bilinear weakly contractive systems that entrain to periodic
excitations. Entrainment is important in many natural and artificial processes. For example …
excitations. Entrainment is important in many natural and artificial processes. For example …
Embedded Extremum Seeking: A Bio-synthetic Optimiser
In cybergentics, internal control uses synthetic genetic circuits to bypass the sensing and
actuation limits of external control. Currently, embedded controllers are limited to basic …
actuation limits of external control. Currently, embedded controllers are limited to basic …
Systems with integral resource consumption
Systems in which a control action can only be taken when a certain resource η is available
can be found in various applications, ie in biological, engineering and economic sciences. In …
can be found in various applications, ie in biological, engineering and economic sciences. In …