The role of neutrophil extracellular traps in acute lung injury
Acute lung injury (ALI) is a heterogeneous inflammatory condition associated with high
morbidity and mortality. Neutrophils play a key role in the development of different forms of …
morbidity and mortality. Neutrophils play a key role in the development of different forms of …
The inflammatory response to extracorporeal membrane oxygenation (ECMO): a review of the pathophysiology
Extracorporeal membrane oxygenation (ECMO) is a technology capable of providing short-
term mechanical support to the heart, lungs or both. Over the last decade, the number of …
term mechanical support to the heart, lungs or both. Over the last decade, the number of …
Mechanisms of lung ischemia-reperfusion injury
Methods for prevention of primary graft dysfunction after lung transplant are urgently
needed, and understanding mechanisms of ischemia-reperfusion injury is critical for the …
needed, and understanding mechanisms of ischemia-reperfusion injury is critical for the …
Neutrophil extracellular traps are pathogenic in primary graft dysfunction after lung transplantation
Rationale: Primary graft dysfunction (PGD) causes early mortality after lung transplantation
and may contribute to late graft failure. No effective treatments exist. The pathogenesis of …
and may contribute to late graft failure. No effective treatments exist. The pathogenesis of …
Neutrophils—a key component of ischemia-reperfusion injury
Ischemia-reperfusion injury (IRI) is a common occurrence following myocardial infarction,
transplantation, stroke, and trauma that can lead to multiple organ failure, which remains the …
transplantation, stroke, and trauma that can lead to multiple organ failure, which remains the …
Postconditioning with Irisin Attenuates Lung Ischemia/Reperfusion Injury by Suppressing Ferroptosis via Induction of the Nrf2/HO‐1 Signal Axis
Y Wang, Z Dong, Z Zhang, Y Wang… - … medicine and cellular …, 2022 - Wiley Online Library
Iron‐dependent lipid peroxidation causes ferroptosis. This study was aimed at verifying that
irisin postconditioning can inhibit ferroptosis and minimize lung ischemia/reperfusion (I/R) …
irisin postconditioning can inhibit ferroptosis and minimize lung ischemia/reperfusion (I/R) …
Pulmonary complications of cardiac surgery
TG Tanner, MO Colvin - Lung, 2020 - Springer
Cardiothoracic surgery posits an arrangement of large, significant hemodynamic, and
physiologic alterations upon the human body, which predisposes a patient to develop …
physiologic alterations upon the human body, which predisposes a patient to develop …
DPP4 inhibition by sitagliptin attenuates LPS-induced lung injury in mice
Acute respiratory distress syndrome (ARDS) is a severe clinical condition marked by acute
respiratory failure and dysregulated inflammation. Pulmonary vascular endothelial cells …
respiratory failure and dysregulated inflammation. Pulmonary vascular endothelial cells …
Role of hydrogen sulfide in ischemia‐reperfusion injury
Ischemia‐reperfusion (I/R) injury is one of the major causes of high morbidity, disability, and
mortality in the world. I/R injury remains a complicated and unresolved situation in clinical …
mortality in the world. I/R injury remains a complicated and unresolved situation in clinical …
Recent advances in the NEK7-licensed NLRP3 inflammasome activation: Mechanisms, role in diseases and related inhibitors
N Zhao, C Li, B Di, L Xu - Journal of autoimmunity, 2020 - Elsevier
Highlights•NEK7 is a vital component involved in the NLRP3 inflammasome
activation.•NEK7-licensed NLRP3 inflammasome activation includes multiple …
activation.•NEK7-licensed NLRP3 inflammasome activation includes multiple …