Oxidative stress (OS), defined as redox imbalance in favor of oxidant burden, is one of the
most significant biological events in cancer progression. Cancer cells generally represent a …

Drug‐induced toxicity is a key issue for public health because some side effects can be
severe and life‐threatening. These adverse effects can also be a major concern for the …

Background: The body of evidence available from published literature during the past three
decades indicates that reactive oxygen species and reactive nitrogen species can induce …

Arsenic and antimony are coexisting cumulative environmental pollutants that cause severe
and extensive biological toxicity. However, their interactions and toxic mechanisms in the …

Arsenic is a naturally occurring element with a long history of toxicity. Sites of contamination
are found worldwide as a result of both natural processes and anthropogenic activities. The …

Cadmium is a heavy metal that has been shown to cause its toxicity in humans and animals.
Many documented studies have shown that cadmium produces various genotoxic effects …

Human exposure to inorganic arsenic (iAs) is a global health issue. Although there is strong
evidence for iAs‐induced toxicity at higher levels of exposure, many epidemiological studies …

Oxidative stress (OS) has been characterized by an imbalance between the production of
reactive oxygen species (ROS) and a biological system's ability to repair oxidative damage …

Acute myeloid leukemias (AML) are a group of aggressive hematologic malignancies
resulting from acquired genetic mutations in hematopoietic stem cells that affect patients of …

Despite having a rich history as a poison, arsenic and its compounds have also gained a
great reputation as promising anticancer drugs. As a pioneer, arsenic trioxide has been …