Deep learning in histopathology: the path to the clinic

J Van der Laak, G Litjens, F Ciompi - Nature medicine, 2021 - nature.com
Abstract Machine learning techniques have great potential to improve medical diagnostics,
offering ways to improve accuracy, reproducibility and speed, and to ease workloads for …

Deep learning in cancer pathology: a new generation of clinical biomarkers

A Echle, NT Rindtorff, TJ Brinker, T Luedde… - British journal of …, 2021 - nature.com
Clinical workflows in oncology rely on predictive and prognostic molecular biomarkers.
However, the growing number of these complex biomarkers tends to increase the cost and …

Dtfd-mil: Double-tier feature distillation multiple instance learning for histopathology whole slide image classification

H Zhang, Y Meng, Y Zhao, Y Qiao… - Proceedings of the …, 2022 - openaccess.thecvf.com
Multiple instance learning (MIL) has been increasingly used in the classification of
histopathology whole slide images (WSIs). However, MIL approaches for this specific …

Transmil: Transformer based correlated multiple instance learning for whole slide image classification

Z Shao, H Bian, Y Chen, Y Wang… - Advances in neural …, 2021 - proceedings.neurips.cc
Multiple instance learning (MIL) is a powerful tool to solve the weakly supervised
classification in whole slide image (WSI) based pathology diagnosis. However, the current …

Designing deep learning studies in cancer diagnostics

A Kleppe, OJ Skrede, S De Raedt, K Liestøl… - Nature Reviews …, 2021 - nature.com
The number of publications on deep learning for cancer diagnostics is rapidly increasing,
and systems are frequently claimed to perform comparable with or better than clinicians …

Whole slide images based cancer survival prediction using attention guided deep multiple instance learning networks

J Yao, X Zhu, J Jonnagaddala, N Hawkins… - Medical Image Analysis, 2020 - Elsevier
Traditional image-based survival prediction models rely on discriminative patch labeling
which make those methods not scalable to extend to large datasets. Recent studies have …

Deep neural network models for computational histopathology: A survey

CL Srinidhi, O Ciga, AL Martel - Medical image analysis, 2021 - Elsevier
Histopathological images contain rich phenotypic information that can be used to monitor
underlying mechanisms contributing to disease progression and patient survival outcomes …

Benchmarking weakly-supervised deep learning pipelines for whole slide classification in computational pathology

NG Laleh, HS Muti, CML Loeffler, A Echle… - Medical image …, 2022 - Elsevier
Artificial intelligence (AI) can extract visual information from histopathological slides and
yield biological insight and clinical biomarkers. Whole slide images are cut into thousands of …

An annotation-free whole-slide training approach to pathological classification of lung cancer types using deep learning

CL Chen, CC Chen, WH Yu, SH Chen… - Nature …, 2021 - nature.com
Deep learning for digital pathology is hindered by the extremely high spatial resolution of
whole-slide images (WSIs). Most studies have employed patch-based methods, which often …

Medical image analysis based on deep learning approach

M Puttagunta, S Ravi - Multimedia tools and applications, 2021 - Springer
Medical imaging plays a significant role in different clinical applications such as medical
procedures used for early detection, monitoring, diagnosis, and treatment evaluation of …