The state of lipid rafts: from model membranes to cells
M Edidin - Annual review of biophysics and biomolecular …, 2003 - annualreviews.org
▪ Abstract Lipid raft microdomains were conceived as part of a mechanism for the
intracellular trafficking of lipids and lipid-anchored proteins. The raft hypothesis is based on …
intracellular trafficking of lipids and lipid-anchored proteins. The raft hypothesis is based on …
[HTML][HTML] Seeing spots: complex phase behavior in simple membranes
Liquid domains in model lipid bilayers are frequently studied as models of raft domains in
cell plasma membranes. Micron-scale liquid domains are easily produced in vesicles …
cell plasma membranes. Micron-scale liquid domains are easily produced in vesicles …
[HTML][HTML] Separation of liquid phases in giant vesicles of ternary mixtures of phospholipids and cholesterol
We use fluorescence microscopy to directly observe liquid phases in giant unilamellar
vesicles. We find that a long list of ternary mixtures of high melting temperature (saturated) …
vesicles. We find that a long list of ternary mixtures of high melting temperature (saturated) …
[HTML][HTML] Sphingomyelin/phosphatidylcholine/cholesterol phase diagram: boundaries and composition of lipid rafts
The ternary system palmitoylsphingomyelin (PSM)/palmitoyloleoylphosphatidylcholine
(POPC)/cholesterol is used to model lipid rafts. The phase behavior of the three binary …
(POPC)/cholesterol is used to model lipid rafts. The phase behavior of the three binary …
High cholesterol/low cholesterol: effects in biological membranes: a review
WK Subczynski, M Pasenkiewicz-Gierula… - Cell biochemistry and …, 2017 - Springer
Lipid composition determines membrane properties, and cholesterol plays a major role in
this determination as it regulates membrane fluidity and permeability, as well as induces the …
this determination as it regulates membrane fluidity and permeability, as well as induces the …
Cellular engulfment and uptake of macromolecular assemblies or nanoparticles via
endocytosis can be associated to both healthy and disease-related biological processes as …
endocytosis can be associated to both healthy and disease-related biological processes as …
Lipid rafts have different sizes depending on membrane composition: a time-resolved fluorescence resonance energy transfer study
The ternary lipid system palmitoylsphingomyelin (PSM)/palmitoyloleoylphosphatidylcholine
(POPC)/cholesterol is a model for lipid rafts. Previously the phase diagram for that mixture …
(POPC)/cholesterol is a model for lipid rafts. Previously the phase diagram for that mixture …
Phase diagrams of lipid mixtures relevant to the study of membrane rafts
The present paper reviews the phase properties of phosphatidylcholine–sphingomyelin–
cholesterol mixtures, that are often used as models for membrane “raft” microdomains. The …
cholesterol mixtures, that are often used as models for membrane “raft” microdomains. The …