Current advance of nanotechnology in diagnosis and treatment for malignant tumors

B Wang, S Hu, Y Teng, J Chen, H Wang, Y Xu… - … and Targeted Therapy, 2024 - nature.com
Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …

Revolutionizing cancer monitoring with carbon-based electrochemical biosensors

F Karimi, H Karimi-Maleh, J Rouhi, N Zare… - Environmental …, 2023 - Elsevier
Cancer monitoring plays a critical role in improving patient outcomes by providing early
detection, personalized treatment options, and treatment response tracking. Carbon-based …

[HTML][HTML] Reactive oxygen species trigger NF-κB-mediated NLRP3 inflammasome activation involvement in low-dose CdTe QDs exposure-induced hepatotoxicity

Y Pang, D Wu, Y Ma, Y Cao, Q Liu, M Tang, Y Pu… - Redox Biology, 2021 - Elsevier
Cadmium telluride (CdTe) quantum dots (QDs) can be employed as imaging and drug
delivery tools; however, the toxic effects and mechanisms of low-dose exposure are unclear …

Comparative study of cathepsin B-cleavable linkers for the optimal design of cathepsin B-specific doxorubicin prodrug nanoparticles for targeted cancer therapy

N Shim, SI Jeon, S Yang, JY Park, M Jo, J Kim, J Choi… - Biomaterials, 2022 - Elsevier
A carrier-free prodrug nanoparticle has emerged as a potential approach to cancer therapy.
It plays a vital role in enhancing the tumor targeting and therapeutic efficacy of the …

Nanosafety: an evolving concept to bring the safest possible nanomaterials to society and environment

F Lebre, N Chatterjee, S Costa… - Nanomaterials, 2022 - mdpi.com
The use of nanomaterials has been increasing in recent times, and they are widely used in
industries such as cosmetics, drugs, food, water treatment, and agriculture. The rapid …

Nanomaterials-induced toxicity on cardiac myocytes and tissues, and emerging toxicity assessment techniques

Y Cheng, Z Chen, S Yang, T Liu, L Yin, Y Pu… - Science of The Total …, 2021 - Elsevier
The extensive production and use of nanomaterials have resulted in the continuous release
of nano-sized particles into the environment, and the health risks caused by exposure to …

Proteomics revealed composition-and size-related regulators for hepatic impairments induced by silica nanoparticles

X Zhao, R Ma, A Abulikemu, Y Qi, X Liu, J Wang… - Science of The Total …, 2024 - Elsevier
Along with the growing production and application of silica nanoparticles (SiNPs), increased
human exposure and ensuing safety evaluation have progressively attracted concern …

MnO2 nanoparticles trigger hepatic lipotoxicity and mitophagy via mtROS-dependent Hsf1Ser326 phosphorylation

T Zhao, H Zheng, JJ Xu, K Pantopoulos, YC Xu… - Free Radical Biology …, 2024 - Elsevier
Manganese (Mn) is an essential element for maintaining normal metabolism in vertebrates.
Mn dioxide nanoparticles (MnO 2 NPs), a novel Mn source, have shown great potentials in …

Combating tumor PARP inhibitor resistance: Combination treatments, nanotechnology, and other potential strategies

R Wang, Y Liu, M Liu, M Zhang, C Li, S Xu… - International Journal of …, 2024 - Elsevier
Abstract PARP (poly (ADP-ribose) polymerase) inhibitors (PARPi) have demonstrated
significant potential in cancer treatment, particularly in tumors with breast cancer …

Nanostructured lipid carriers for enhanced batimastat delivery across the blood–brain barrier: an in vitro study for glioblastoma treatment

M Horta, P Soares, B Sarmento, C Leite Pereira… - Drug Delivery and …, 2025 - Springer
Glioblastoma presents a significant treatment challenge due to the blood–brain barrier
(BBB) hindering drug delivery, and the overexpression of matrix metalloproteinases (MMPs) …