The foreign body reaction composed of macrophages and foreign body giant cells is the end-
stage response of the inflammatory and wound healing responses following implantation of …

Bone homeostasis is securely controlled by the dynamic well‐balanced actions among
osteoclasts, osteoblasts and osteocytes. Osteoclasts are large multinucleated cells that …

Obesity alters adipose tissue metabolic and endocrine function and leads to an increased
release of fatty acids, hormones, and proinflammatory molecules that contribute to obesity …

Textbook and Color Atlas of Traumatic Injuries to the Teeth, Fifth Edition encompasses the
full scope of acute dental trauma, including all aspects of interdisciplinary treatment. This …

I. Introduction B ONE is a complex tissue in which resorption and formation continue
throughout life. This process is called bone remodeling. Osteotropic hormones such as 1α …

Interleukin-6 (IL-6) and interleukin-11 (IL-11) are known to influence osteoclast formation
and bone resorption. In order to determine whether IL-6 and IL-11 could independently …

Introduction The interaction between the immune and skeletal systems is evidenced by the
bone loss observed in autoimmune diseases such as rheumatoid arthritis. In this paper we …

Both human and murine osteoclasts can be derived in vitro from hematopoietic cells or
monocytes that are cocultured with osteoblasts or marrow-derived stromal cells. The …

This chapter focuses on recent developments in our understanding of in vitro and in vivo
monocyte, macrophage, foreign body giant cell (FBGC), and lymphocyte interactions with …

The osteoclast is known to be formed by fusion of circulating mononuclear precursor cells of
haematopoietic origin. The precise nature of these circulating cells and, in particular, their …