Nanoparticles (NPs) have emerged as an effective modality for the treatment of various
diseases including cancer, cardiovascular and inflammatory diseases. Various forms of NPs …

Nanoparticles have demonstrated significant advancements in potential oral delivery of
insulin. In this publication, we review the current status of polymeric, inorganic and solid-lipid …

Mucus is a viscoelastic biological hydrogel that protects the epithelial surface from
penetration by most nanoparticles, which limits the efficiency of oral drug delivery. Pursuing …

To optimally penetrate biological hydrogels such as mucus and the tumor interstitial matrix,
nanoparticles (NPs) require physicochemical properties that would typically preclude …

Compared to subcutaneous injections, oral administration of insulin would be a preferred
route of drug administration for diabetic patients. For oral delivery, both liposomes and …

Diabetes mellitus, an incurable metabolic disease, is characterized by changes in the
homeostasis of blood sugar levels, being the subcutaneous injection of insulin the first line …

Oral administration of protein drugs is greatly impeded by the lack of drug carriers that can
efficiently overcome the absorption barriers of mucosa tissue, which consists of not only …

Peptide drugs play an important role in diabetes mellitus treatment. Oral administration of
peptide drugs is a promising strategy for diabetes mellitus because of its convenience and …

The oral route has long been recognized as the most preferred route for drug delivery as it
offers high patient compliance and requires minimal expertise. Unlike small molecule drugs …

Mucus is a complex viscoelastic gel and acts as a barrier covering much of the soft tissue in
the human body. High vascularization and accessibility have motivated drug delivery to …