Principles, approaches, and challenges for predicting protein aggregation rates and shelf life

WF Weiss IV, TM Young, CJ Roberts - Journal of pharmaceutical sciences, 2009 - Elsevier
Control and prevention of unwanted aggregation for therapeutic proteins is a ubiquitous
hurdle during biopharmaceutical product manufacture, storage, ship**, and …

A molecular-thermodynamic model for the interactions between globular proteins in aqueous solutions: Applications to bovine serum albumin (BSA), lysozyme, α …

L **, YX Yu, GH Gao - Journal of colloid and interface science, 2006 - Elsevier
To investigate globular protein–protein and protein–salt interactions in electrolyte solutions,
a potential of mean force including hard-core repulsion, van der Waals attraction and electric …

Prediction of collective diffusion coefficient of bovine serum albumin in aqueous electrolyte solution with hard-core two-Yukawa potential

YX Yu, AW Tian, GH Gao - Physical Chemistry Chemical Physics, 2005 - pubs.rsc.org
A new method to predict concentration dependence of collective diffusion coefficient of
bovine serum albumin (BSA) in aqueous electrolyte solution is developed based on the …

Monte Carlo simulation for the hard-core two-Yukawa fluids and test of the two-Yukawa equation of state

YZ Lin, YG Li, JF Lu, W Wu - The Journal of chemical physics, 2002 - pubs.aip.org
A recently proposed analytical equation of state (EOS) for the hard-core two-Yukawa fluids is
tested against the results of Monte Carlo (MC) simulation in six cases. One range parameter …

Simple analytic equations of state for hard-core single and double Yukawa fluids and mixtures based on second-order Barker-Henderson perturbation theory

S Jiuxun - Physical Review E, 2003 - APS
A simple analytic expression with high precision for the radial distribution function of hard
spheres is proposed. The form of the expression has been carefully selected to combine the …

Thermodynamic and structural properties of repulsive hard-core Yukawa fluid: Integral equation theory, perturbation theory and Monte Carlo simulations

TW Cochran, YC Chiew - The Journal of chemical physics, 2004 - pubs.aip.org
The Yukawa hard sphere system is a molecular model that has received considerable
attention in recent years. Theoretical and computer simulation studies have been carried out …

Study on multi-Yukawa potential between charged colloid particles

YZ Lin, YG Li, JD Li - Journal of molecular liquids, 2006 - Elsevier
The Yukawa potential has the function to express both the attractive dispersion interaction
and the double-layer repulsive electrostatic interaction. In this paper, a comprehensive …

Study on analytical solutions and their simplification for one-component multi-Yukawa fluids and test by Monte-Carlo simulation

YZ Lin, YG Li, JF Lu - Molecular Physics, 2004 - Taylor & Francis
Using the mean spherical approximation, an explicit analytical equation of state with non-
dimensional variables for one-component multi-Yukawa fluids is established based on the …

Structure of hard-core Yukawa fluid mixtures near a semi-permeable membrane: A density functional study

Z Yang, X Yang, Z Xu - Journal of Membrane Science, 2008 - Elsevier
The density profiles of binary attractive and binary repulsive hard-core Yukawa (HCY) fluid
mixtures with the screening factor λ= 1.8 near a semi-permeable membrane have been …

High-temperature expansion of the mean spherical approximation for hard-core two-Yukawa simple and chain fluids

H Guérin - Fluid phase equilibria, 2004 - Elsevier
Analytic compressibility factors and internal energies for hard-core two-Yukawa (HCTY)
simple fluids are obtained by using the high-temperature expansion of the mean spherical …