[HTML][HTML] The role and specific mechanism of OCT4 in cancer stem cells: a review

Q Zhang, Z Han, Y Zhu, J Chen… - International journal of …, 2020 - synapse.koreamed.org
Recently, evidences show that cancer stem cells (CSCs) are a type of cancer cell group with
self-renewal and play a huge role in tumor recurrence, metastasis, and drug resistance …

Cancer stem cells: a target for overcoming therapeutic resistance and relapse

S Zhang, R Yang, Y Ouyang, Y Shen… - Cancer Biology & …, 2024 - pmc.ncbi.nlm.nih.gov
Cancer stem cells (CSCs) are a small subset of cells in cancers that are thought to initiate
tumorous transformation and promote metastasis, recurrence, and resistance to treatment …

NANOG decoy oligodeoxynucleotide–encapsulated niosomes nanocarriers: a promising approach to suppress the metastatic properties of U87 human glioblastoma …

M Gharbavi, B Johari, E Rismani… - ACS Chemical …, 2020 - ACS Publications
Recently, advances in the synthesis and development of multifunctional nanoparticle
platforms have opened up great opportunities and advantages for specifically targeted …

[HTML][HTML] Combinational therapy with Myc decoy oligodeoxynucleotides encapsulated in nanocarrier and X-irradiation on breast cancer cells

B Johari, MP Leilan, M Gharbavi… - Oncology …, 2023 - pmc.ncbi.nlm.nih.gov
The Myc gene is the essential oncogene in triple-negative breast cancer (TNBC). This study
investigates the synergistic effects of combining Myc decoy oligodeoxynucleotides …

[HTML][HTML] Targeting of human cancer stem cells predicts efficacy and toxicity of FDA-approved oncology drugs

K Vojnits, Z Feng, P Johnson, D Porras, E Manocha… - Cancer Letters, 2024 - Elsevier
Cancer remains the leading cause of death worldwide with approved oncology drugs
continuing to have heterogenous patient responses and accompanied adverse effects (AEs) …

MicroRNAs regulating SOX2 in cancer progression and therapy response

S Mirzaei, H Saebfar, MH Gholami… - Expert reviews in …, 2021 - cambridge.org
The proliferation, metastasis and therapy response of tumour cells are tightly regulated by
interaction among various signalling networks. The microRNAs (miRNAs) can bind to 3 …

Suppress the cell growth of cancer stem-like cells (NTERA-2) using Sox2-Oct4 decoy oligodeoxynucleotide− encapsulated niosomes-zinc hybrid nanocarriers under X …

B Johari, S Tavangar-Roosta, M Gharbavi, A Sharafi… - Heliyon, 2024 - cell.com
Sox2 and Oct4 dysregulations could significantly increase in the cancer stem cell (CSC)
population in some cancer cells and resistance to common treatments. In this study, the …

Sulforaphane regulates the proliferation of leukemia stem-like cells via Sonic Hedgehog signaling pathway

F Wang, X Huang, Y Sun, Z Li, R Sun, T Zhao… - European Journal of …, 2022 - Elsevier
Sulforaphane (SFN), the main ingredient in broccoli/broccoli sprouts, has a good anticancer
effect in a wide variety of tumors, but whether SFN affects acute leukemia is not elucidated …

Application of transcription factor decoy oligodeoxynucleotides (ODNs) for cancer therapy

B Johari, M Moradi - Gene Therapy of Cancer: Methods and Protocols, 2022 - Springer
As a method of gene therapy, application of decoy oligodeoxynucleotides (ODNs) could
interfere at the pretranscription level, by blocking the transcription factors, and inhibiting their …

Evaluation of STAT3 decoy oligodeoxynucleotides' synergistic effects on radiation and/or chemotherapy in metastatic breast cancer cell line

B Johari, M Rahmati, L Nasehi… - Cell Biology …, 2020 - Wiley Online Library
Resistance to radiotherapy and chemotherapy has been a major problem of conventional
cancer therapies, which consequently leads to cancer relapse and cancer‐related death. It …