[HTML][HTML] The role and specific mechanism of OCT4 in cancer stem cells: a review
Q Zhang, Z Han, Y Zhu, J Chen… - International journal of …, 2020 - synapse.koreamed.org
Recently, evidences show that cancer stem cells (CSCs) are a type of cancer cell group with
self-renewal and play a huge role in tumor recurrence, metastasis, and drug resistance …
self-renewal and play a huge role in tumor recurrence, metastasis, and drug resistance …
Cancer stem cells: a target for overcoming therapeutic resistance and relapse
S Zhang, R Yang, Y Ouyang, Y Shen… - Cancer Biology & …, 2024 - pmc.ncbi.nlm.nih.gov
Cancer stem cells (CSCs) are a small subset of cells in cancers that are thought to initiate
tumorous transformation and promote metastasis, recurrence, and resistance to treatment …
tumorous transformation and promote metastasis, recurrence, and resistance to treatment …
NANOG decoy oligodeoxynucleotide–encapsulated niosomes nanocarriers: a promising approach to suppress the metastatic properties of U87 human glioblastoma …
Recently, advances in the synthesis and development of multifunctional nanoparticle
platforms have opened up great opportunities and advantages for specifically targeted …
platforms have opened up great opportunities and advantages for specifically targeted …
[HTML][HTML] Combinational therapy with Myc decoy oligodeoxynucleotides encapsulated in nanocarrier and X-irradiation on breast cancer cells
The Myc gene is the essential oncogene in triple-negative breast cancer (TNBC). This study
investigates the synergistic effects of combining Myc decoy oligodeoxynucleotides …
investigates the synergistic effects of combining Myc decoy oligodeoxynucleotides …
[HTML][HTML] Targeting of human cancer stem cells predicts efficacy and toxicity of FDA-approved oncology drugs
K Vojnits, Z Feng, P Johnson, D Porras, E Manocha… - Cancer Letters, 2024 - Elsevier
Cancer remains the leading cause of death worldwide with approved oncology drugs
continuing to have heterogenous patient responses and accompanied adverse effects (AEs) …
continuing to have heterogenous patient responses and accompanied adverse effects (AEs) …
MicroRNAs regulating SOX2 in cancer progression and therapy response
The proliferation, metastasis and therapy response of tumour cells are tightly regulated by
interaction among various signalling networks. The microRNAs (miRNAs) can bind to 3 …
interaction among various signalling networks. The microRNAs (miRNAs) can bind to 3 …
Suppress the cell growth of cancer stem-like cells (NTERA-2) using Sox2-Oct4 decoy oligodeoxynucleotide− encapsulated niosomes-zinc hybrid nanocarriers under X …
Sox2 and Oct4 dysregulations could significantly increase in the cancer stem cell (CSC)
population in some cancer cells and resistance to common treatments. In this study, the …
population in some cancer cells and resistance to common treatments. In this study, the …
Sulforaphane regulates the proliferation of leukemia stem-like cells via Sonic Hedgehog signaling pathway
F Wang, X Huang, Y Sun, Z Li, R Sun, T Zhao… - European Journal of …, 2022 - Elsevier
Sulforaphane (SFN), the main ingredient in broccoli/broccoli sprouts, has a good anticancer
effect in a wide variety of tumors, but whether SFN affects acute leukemia is not elucidated …
effect in a wide variety of tumors, but whether SFN affects acute leukemia is not elucidated …
Application of transcription factor decoy oligodeoxynucleotides (ODNs) for cancer therapy
As a method of gene therapy, application of decoy oligodeoxynucleotides (ODNs) could
interfere at the pretranscription level, by blocking the transcription factors, and inhibiting their …
interfere at the pretranscription level, by blocking the transcription factors, and inhibiting their …
Evaluation of STAT3 decoy oligodeoxynucleotides' synergistic effects on radiation and/or chemotherapy in metastatic breast cancer cell line
Resistance to radiotherapy and chemotherapy has been a major problem of conventional
cancer therapies, which consequently leads to cancer relapse and cancer‐related death. It …
cancer therapies, which consequently leads to cancer relapse and cancer‐related death. It …