Next-generation sequencing: insights to advance clinical investigations of the microbiome
Next-generation sequencing (NGS) technology has advanced our understanding of the
human microbiome by allowing for the discovery and characterization of unculturable …
human microbiome by allowing for the discovery and characterization of unculturable …
The gut microbiota and its biogeography
G McCallum, C Tropini - Nature Reviews Microbiology, 2024 - nature.com
Biogeography is the study of species distribution and diversity within an ecosystem and is at
the core of how we understand ecosystem dynamics and interactions at the macroscale. In …
the core of how we understand ecosystem dynamics and interactions at the macroscale. In …
The person-to-person transmission landscape of the gut and oral microbiomes
The human microbiome is an integral component of the human body and a co-determinant
of several health conditions,. However, the extent to which interpersonal relations shape the …
of several health conditions,. However, the extent to which interpersonal relations shape the …
inStrain profiles population microdiversity from metagenomic data and sensitively detects shared microbial strains
Coexisting microbial cells of the same species often exhibit genetic variation that can affect
phenotypes ranging from nutrient preference to pathogenicity. Here we present inStrain, a …
phenotypes ranging from nutrient preference to pathogenicity. Here we present inStrain, a …
Clinical metagenomics
CY Chiu, SA Miller - Nature Reviews Genetics, 2019 - nature.com
Clinical metagenomic next-generation sequencing (mNGS), the comprehensive analysis of
microbial and host genetic material (DNA and RNA) in samples from patients, is rapidly …
microbial and host genetic material (DNA and RNA) in samples from patients, is rapidly …
Circadian rhythms and the gut microbiota: from the metabolic syndrome to cancer
The metabolic syndrome is prevalent in developed nations and accounts for the largest
burden of non-communicable diseases worldwide. The metabolic syndrome has direct …
burden of non-communicable diseases worldwide. The metabolic syndrome has direct …
MetaWRAP—a flexible pipeline for genome-resolved metagenomic data analysis
Background The study of microbiomes using whole-metagenome shotgun sequencing
enables the analysis of uncultivated microbial populations that may have important roles in …
enables the analysis of uncultivated microbial populations that may have important roles in …
Health benefits of heat-killed (Tyndallized) probiotics: an overview
Nowadays, the oral use of probiotics is widespread. However, the safety profile with the use
of live probiotics is still a matter of debate. Main risks include: Cases of systemic infections …
of live probiotics is still a matter of debate. Main risks include: Cases of systemic infections …
Culturing the human microbiota and culturomics
The gut microbiota has an important role in the maintenance of human health and in disease
pathogenesis. This importance was realized through the advent of omics technologies and …
pathogenesis. This importance was realized through the advent of omics technologies and …
[HTML][HTML] Effects of psychological, environmental and physical stressors on the gut microbiota
JP Karl, AM Hatch, SM Arcidiacono… - Frontiers in …, 2018 - frontiersin.org
Stress, a ubiquitous part of daily human life, has varied biological effects which are
increasingly recognized as including modulation of commensal microorganisms residing in …
increasingly recognized as including modulation of commensal microorganisms residing in …