Immunoinformatics and vaccine development: an overview

AN Oli, WO Obialor, MO Ifeanyichukwu… - ImmunoTargets and …, 2020‏ - Taylor & Francis
The use of vaccines have resulted in a remarkable improvement in global health. It has
saved several lives, reduced treatment costs and raised the quality of animal and human …

Exploring Klebsiella pneumoniae capsule polysaccharide proteins to design multiepitope subunit vaccine to fight against pneumonia

J Dey, SR Mahapatra, S Lata, S Patro… - Expert Review of …, 2022‏ - Taylor & Francis
Background Klebsiella pneumoniae is an emerging human pathogen causing neonatal lung
disease, catheter-associated infections, and nosocomial outbreaks with high fatality rates …

In-silico design of a multi-epitope vaccine candidate against onchocerciasis and related filarial diseases

RA Shey, SM Ghogomu, KK Esoh, ND Nebangwa… - Scientific reports, 2019‏ - nature.com
Onchocerciasis is a parasitic disease with high socio-economic burden particularly in sub-
Saharan Africa. The elimination plan for this disease has faced numerous challenges. A …

In silico design and immunoinformatics analysis of a universal multi-epitope vaccine against monkeypox virus

S Sanami, S Nazarian, S Ahmad, E Raeisi… - Plos one, 2023‏ - journals.plos.org
Monkeypox virus (MPXV) outbreaks have been reported in various countries worldwide;
however, there is no specific vaccine against MPXV. In this study, therefore, we employed …

In silico analysis of epitope-based vaccine candidate against tuberculosis using reverse vaccinology

S Bibi, I Ullah, B Zhu, M Adnan, R Liaqat, WB Kong… - Scientific reports, 2021‏ - nature.com
Tuberculosis (TB) kills more individuals in the world than any other disease, and a threat
made direr by the coverage of drug-resistant strains of Mycobacterium tuberculosis (Mtb) …

Designing a multi-epitope vaccine against SARS-CoV-2: an immunoinformatics approach

A Samad, F Ahammad, Z Nain, R Alam… - Journal of …, 2022‏ - Taylor & Francis
Ongoing COVID-19 outbreak has raised a drastic challenge to global public health security.
Most of the patients with COVID-19 suffer from mild flu-like illnesses such as cold and fever; …

Designing multi-epitope vaccine against Staphylococcus aureus by employing subtractive proteomics, reverse vaccinology and immuno-informatics approaches

MT ul Qamar, S Ahmad, I Fatima, F Ahmad… - Computers in Biology …, 2021‏ - Elsevier
Staphylococcus aureus is a deadly human bacterial pathogen that causes a wide variety of
clinical manifestations. Invasive S. aureus infections in hospitals and the community are one …

Novel Immunoinformatics Approaches to Design Multi-epitope Subunit Vaccine for Malaria by Investigating Anopheles Salivary Protein

RK Pandey, TK Bhatt, VK Prajapati - Scientific reports, 2018‏ - nature.com
Malaria fever has been pervasive for quite a while in tropical develo** regions causing
high morbidity and mortality. The causal organism is a protozoan parasite of genus …

Designing of a next generation multiepitope based vaccine (MEV) against SARS-COV-2: Immunoinformatics and in silico approaches

M Tahir ul Qamar, A Rehman, K Tusleem, UA Ashfaq… - PloS one, 2020‏ - journals.plos.org
Coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory
coronavirus 2 (SARS-COV-2) is a significant threat to global health security. Till date, no …

Designing a multi-epitope based vaccine to combat Kaposi Sarcoma utilizing immunoinformatics approach

V Chauhan, T Rungta, K Goyal, MP Singh - Scientific reports, 2019‏ - nature.com
Kaposi's sarcoma-associated herpesvirus (KSHV) responsible for causing Kaposi sarcoma
(KS), an opportunistic angioproliferative neoplasm is emerging rapidly. Despite this there is …