Imidazole ring is an important five‐membered aromatic heterocycle widely present in natural
products and synthetic molecules. The unique structural feature of imidazole ring with …

The practice of polypharmacology is not a new concept but the approaches which are being
adopted for administering the two or more drugs together are varied from time to time …

Triazole compounds containing three nitrogen atoms in the five-membered aromatic azole
ring are readily able to bind with a variety of enzymes and receptors in biological system via …

Coumarin compounds represent an important type of naturally occurring and synthetic
oxygen-containing heterocycles with typical benzopyrone framework. This type of special …

A series of novel sulfanilamide-derived 1, 2, 3-triazole compounds were synthesized in
excellent yields via 1, 3-dipolar cycloaddition and confirmed by MS, IR and NMR spectra as …

A series of new coumarin-based 1, 2, 4-triazole derivatives were designed, synthesized and
evaluated for their antimicrobial activities in vitro against four Gram-positive bacteria …

Azole compounds are an important class of nitrogen heterocycles with electron-rich
property. This special structure endows azole-based derivatives easily bind with the …

A series of N-substituted carbazole derivatives were synthesized and evaluated for
antibacterial and antifungal activities against Staphylococcus aureus, methicillin-resistant …

This study contains novel a serie synthesis of N-heterocyclic carbene (NHC) precursors that
2-hydroxyethyl substituted. The NHC precursors have been prepared from 1-(2 …

A series of novel amine-derived bis-azole compounds were designed by the systematical
structural modification of Fluconazole and synthesized by a convenient and efficient method …