Mycobiome diversity: high-throughput sequencing and identification of fungi

RH Nilsson, S Anslan, M Bahram… - Nature Reviews …, 2019 - nature.com
Fungi are major ecological players in both terrestrial and aquatic environments by cycling
organic matter and channelling nutrients across trophic levels. High-throughput sequencing …

A brief history of bioinformatics

J Gauthier, AT Vincent, SJ Charette… - Briefings in …, 2019 - academic.oup.com
It is easy for today's students and researchers to believe that modern bioinformatics
emerged recently to assist next-generation sequencing data analysis. However, the very …

Polyamine metabolism is a central determinant of helper T cell lineage fidelity

DJ Puleston, F Baixauli, DE Sanin, J Edwards-Hicks… - Cell, 2021 - cell.com
Polyamine synthesis represents one of the most profound metabolic changes during T cell
activation, but the biological implications of this are scarcely known. Here, we show that …

[PDF][PDF] pyGenomeTracks: reproducible plots for multivariate genomic datasets

L Lopez-Delisle, L Rabbani, J Wolff, V Bhardwaj… - …, 2021 - academic.oup.com
Motivation Generating publication ready plots to display multiple genomic tracks can pose a
serious challenge. Making desirable and accurate figures requires considerable effort. This …

Cytoscape automation: empowering workflow-based network analysis

D Otasek, JH Morris, J Bouças, AR Pico, B Demchak - Genome biology, 2019 - Springer
Cytoscape is one of the most successful network biology analysis and visualization tools, but
because of its interactive nature, its role in creating reproducible, scalable, and novel …

The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2018 update

E Afgan, D Baker, B Batut, M Van Den Beek… - Nucleic acids …, 2018 - academic.oup.com
Abstract Galaxy (homepage: https://galaxyproject. org, main public server: https://usegalaxy.
org) is a web-based scientific analysis platform used by tens of thousands of scientists …

Bioconda: sustainable and comprehensive software distribution for the life sciences

B Grüning, R Dale, A Sjödin, BA Chapman, J Rowe… - Nature …, 2018 - nature.com
To the Editor: Bioinformatics software comes in a variety of programming languages and
requires diverse installation methods. This heterogeneity makes management of a software …

MEGARes 2.0: a database for classification of antimicrobial drug, biocide and metal resistance determinants in metagenomic sequence data

E Doster, SM Lakin, CJ Dean, C Wolfe… - Nucleic acids …, 2020 - academic.oup.com
Antimicrobial resistance (AMR) is a threat to global public health and the identification of
genetic determinants of AMR is a critical component to epidemiological investigations. High …

iDEP: an integrated web application for differential expression and pathway analysis of RNA-Seq data

SX Ge, EW Son, R Yao - BMC bioinformatics, 2018 - Springer
Background RNA-seq is widely used for transcriptomic profiling, but the bioinformatics
analysis of resultant data can be time-consuming and challenging, especially for biologists …

ImmPort, toward repurposing of open access immunological assay data for translational and clinical research

S Bhattacharya, P Dunn, CG Thomas, B Smith… - Scientific data, 2018 - nature.com
Immunology researchers are beginning to explore the possibilities of reproducibility, reuse
and secondary analyses of immunology data. Open-access datasets are being applied in …