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Associations of oxidative stress and postoperative outcome in liver surgery with an outlook to future potential therapeutic options
Several types of surgical procedures have shown to elicit an inflammatory stress response,
leading to substantial cytokine production and formation of oxygen‐based or nitrogen …
leading to substantial cytokine production and formation of oxygen‐based or nitrogen …
[HTML][HTML] Development of antioxidant COX-2 inhibitors as radioprotective agents for radiation therapy—a hypothesis-driven review
M Laube, T Kniess, J Pietzsch - Antioxidants, 2016 - mdpi.com
Radiation therapy (RT) evolved to be a primary treatment modality for cancer patients.
Unfortunately, the cure or relief of symptoms is still accompanied by radiation-induced side …
Unfortunately, the cure or relief of symptoms is still accompanied by radiation-induced side …
[HTML][HTML] COX-2 expression in hepatocytes improves mitochondrial function after hepatic ischemia-reperfusion injury
M Fuertes-Agudo, M Luque-Tévar, C Cucarella, R Brea… - Antioxidants, 2022 - mdpi.com
Cyclooxygenase 2 (COX-2) is a key enzyme in prostanoid biosynthesis. The constitutive
hepatocyte expression of COX-2 has a protective role in hepatic ischemia-reperfusion (I/R) …
hepatocyte expression of COX-2 has a protective role in hepatic ischemia-reperfusion (I/R) …
Hyaluronic acid–nimesulide conjugates as anticancer drugs against CD44-overexpressing HT-29 colorectal cancer in vitro and in vivo
YS Jian, CW Chen, CA Lin, HP Yu, HY Lin… - International Journal …, 2017 - Taylor & Francis
Carrier-mediated drug delivery systems are promising therapeutics for targeted delivery and
improved efficacy and safety of potent cytotoxic drugs. Nimesulide is a multifactorial …
improved efficacy and safety of potent cytotoxic drugs. Nimesulide is a multifactorial …
Preconditioning methods in the management of hepatic ischemia reperfusion‐induced injury: Update on molecular and future perspectives
Hepatic IR (ischemia reperfusion) injury is a commonly encountered obstacle in the post‐
operative management of hepatic surgery. Hepatic IR occurs during 'Pringle maneuver'for …
operative management of hepatic surgery. Hepatic IR occurs during 'Pringle maneuver'for …
The propolis and boric acid can be highly suitable, alone/or as a combinatory approach on ovary ischemia-reperfusion injury
Purpose Ovarian ischemia-reperfusion (IR) damage continues to be a serious infertility
problem. The oxidative stress plays central role in the development of IR injuries. Activation …
problem. The oxidative stress plays central role in the development of IR injuries. Activation …
Effect of tocilizumab on ischemia-reperfusion-induced oxido-inflammatory renal damage and dysfunction in rats
KTO Erdem, Z Bedir, U Kuyrukluyildiz, HG Tas… - Experimental …, 2022 - jstage.jst.go.jp
Ischemia-reperfusion-induced (I/R) renal damage is a pathogenic process that starts with
ischemia, then progresses through oxidative stress and inflammation. Tocilizumab (TCZ), a …
ischemia, then progresses through oxidative stress and inflammation. Tocilizumab (TCZ), a …
The Protective Effect of Magnesium Lithospermate B on Hepatic Ischemia/Reperfusion via Inhibiting the Jak2/Stat3 Signaling Pathway
N Zhang, L Han, Y Xue, Q Deng, Z Wu… - Frontiers in …, 2019 - frontiersin.org
Acute inflammation is an important component of the pathogenesis of hepatic
ischemia/reperfusion injury (HIRI). Magnesium lithospermate B (MLB) has strong …
ischemia/reperfusion injury (HIRI). Magnesium lithospermate B (MLB) has strong …
n-3 Fatty acids as resolvents of inflammation in the A549 cells
J Gdula-Argasińska, J Czepiel, A Woźniakiewicz… - Pharmacological …, 2015 - Elsevier
Background Fatty acids and their derivatives are one of the most crucial inflammation
mediators. The aim of our study was to evaluate the impact of polyunsaturated fatty acids as …
mediators. The aim of our study was to evaluate the impact of polyunsaturated fatty acids as …
Effect of lutein on oxidants and proinflammatory cytokine-related liver ischemia-reperfusion injury
© 2022 Polish Pharmaceutical Society. All rights reserved. Lutein has an anti-inflammatory
impact on tissues, according to recent research. The goal of our research was to see how …
impact on tissues, according to recent research. The goal of our research was to see how …