Historically, the thalamus has been viewed as little more than a relay, simply transferring
information to key players of the cast, the cortex and hippocampus, without providing any …

Rats and mice are used for studying neuronal circuits underlying recognition memory due to
their ability to spontaneously remember the occurrence of an object, its place and an …

Standard models of episodic memory focus on hippocampal–parahippocampal interactions,
with the neocortex supplying sensory information and providing a final repository of …

This review brings together current knowledge from tract tracing studies to update and
reconsider those limbic connections initially highlighted by Papez for their presumed role in …

The anterior thalamic nuclei are a vital node within hippocampal-diencephalic-cingulate
circuits that support spatial learning and memory. Reflecting this interconnectivity, the …

After more than 80 years, Papez serial circuit remains a hugely influential concept, initially
for emotion, but in more recent decades, for memory. Here, we show how this circuit is …

Anxiety disorders are currently a major psychiatric and social problem, the mechanisms of
which have been only partially elucidated. The hippocampus serves as a major target of …

The prefrontal cortex (PFC) has a complex relationship with the thalamus, involving many
nuclei which occupy predominantly medial zones along its anterior-to-posterior extent …

Extensive neuroanatomical connectivity between the anterior thalamic nuclei (ATN) and
hippocampus and neocortex renders them well-placed for a role in memory processing, and …

Spatial working memory, the ability to temporarily maintain an internal representation of
spatial information for use in guiding upcoming decisions, has been shown to be dependent …