Enantiomers, where chirality arises from restricted rotation around a single bond, are
atropisomers. Due to the unique nature of the origins of their chirality, synthetic strategies to …

This paper summarizes recent developments in the synthesis, application and mechanistic
studies on polysaccharide-based chiral stationary phases (CSPs) for liquid phase …

Chiral compounds are ubiquitous in nature and play a pivotal role in biochemical processes,
in chiroptical materials and applications, and as chiral drugs. The analysis and …

Chemical reactions that lead to a spontaneous symmetry breaking or amplification of the
enantiomeric excess are of fundamental interest in explaining the formation of a homochiral …

Chirality is one of the key factors affecting the medicinal efficacy of compounds. In addition to
central chirality, sterically hindered chiral axes commonly appear in drugs and the resulting …

We introduce a design principle to stabilize helically chiral structures from an achiral
tetrasubstituted [2.2] paracyclophane by integrating it into a macrocycle. The [2.2] …

An outlook of the various research fields of organic chemistry where conformational analysis
plays a fundamental role is presented. The section Methodologies for Conformational …

The aim of this paper is to introduce the subject of chirality within pharmaceuticals and its
implications in environmental contamination. The paper describes contemporary techniques …

Central-to-axial chirality transfer via C–N single bond oxidation was first achieved as a
versatile and conceptually distinct strategy to prepare a new family of axially chiral …

Three brush-type chiral stationary phases (CSPs) differing in the particle size of the starting
silica particles have been prepared by covalent grafting of the π-acidic bis-(3, 5 …