Stroke is the leading cause of disability and thesecond leading cause of death worldwide.
With the global population aged 65 and over growing faster than all other age groups, the …

Ischemic stroke is one of the leading causes of mortality and disability worldwide. However,
there is a current lack of effective therapies available. As the resident macrophages of the …

Rationale: Microglia play a critical role in modulating cell death and neurobehavioral
recovery in response to brain injury either by direct cell-cell interaction or indirect secretion …

The intrinsic ability of neurogenesis after stroke has been proven weak, which results in
insufficient repair of injury in the nerve system. Recent studies suggest multiple microRNAs …

MicroRNAs (miRNAs) regulate several physiological and pathological processes involved in
various diseases, including osteoarthritis (OA). OA is the most common global …

Inflammatory reactions could be both beneficial and detrimental to the brain, depending on
strengths of their activation in various stages of neurodegeneration. Mild activation of …

Stroke is the second leading cause of global death and is characterized by high rates of
mortality and disability. Oxidative stress is accompanied by other pathological processes …

Central nervous system (CNS) diseases have become one of the leading causes of death in
the global population. The pathogenesis of CNS diseases is complicated, so it is important …

Stroke is a leading cause of disability and mortality, with limited treatment options. After
stroke injury, microglia and CNS‐resident macrophages are rapidly activated and regulate …

Ischemic stroke (IS), a common cerebrovascular disease, results from a sudden blockage of
a blood vessel in the brain, thereby restricting blood supply to the area in question, and …