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[HTML][HTML] Mouse microbiota models: comparing germ-free mice and antibiotics treatment as tools for modifying gut bacteria
As the intestinal microbiota has become better appreciated as necessary for maintenance of
physiologic homeostasis and also as a modulator of disease processes, there has been a …
physiologic homeostasis and also as a modulator of disease processes, there has been a …
The healthy human microbiome
Humans are virtually identical in their genetic makeup, yet the small differences in our DNA
give rise to tremendous phenotypic diversity across the human population. By contrast, the …
give rise to tremendous phenotypic diversity across the human population. By contrast, the …
Laboratory mice born to wild mice have natural microbiota and model human immune responses
INTRODUCTION Laboratory mice are a mainstay of biomedical research and have been
instrumental for many important discoveries in the field of immunology. However, there are …
instrumental for many important discoveries in the field of immunology. However, there are …
Wild mouse gut microbiota promotes host fitness and improves disease resistance
Laboratory mice, while paramount for understanding basic biological phenomena, are
limited in modeling complex diseases of humans and other free-living mammals. Because …
limited in modeling complex diseases of humans and other free-living mammals. Because …
[HTML][HTML] Rebuilding the gut microbiota ecosystem
A microbial ecosystem in which bacteria no longer live in a mutualistic association is called
dysbiotic. Gut microbiota dysbiosis is a condition related with the pathogenesis of intestinal …
dysbiotic. Gut microbiota dysbiosis is a condition related with the pathogenesis of intestinal …
The role of the gut microbiota in NAFLD
NAFLD is now the most common cause of liver disease in Western countries. This Review
explores the links between NAFLD, the metabolic syndrome, dysbiosis, poor diet and gut …
explores the links between NAFLD, the metabolic syndrome, dysbiosis, poor diet and gut …
Characterization of the gut microbiome using 16S or shotgun metagenomics
The advent of next generation sequencing (NGS) has enabled investigations of the gut
microbiome with unprecedented resolution and throughput. This has stimulated the …
microbiome with unprecedented resolution and throughput. This has stimulated the …
[HTML][HTML] Alterations in enteric virome are associated with colorectal cancer and survival outcomes
Background & Aims Patients with colorectal cancer (CRC) have a different gut microbiome
signature than individuals without CRC. Little is known about the viral component of CRC …
signature than individuals without CRC. Little is known about the viral component of CRC …
Disease-specific alterations in the enteric virome in inflammatory bowel disease
Decreases in the diversity of enteric bacterial populations are observed in patients with
Crohn's disease (CD) and ulcerative colitis (UC). Less is known about the virome in these …
Crohn's disease (CD) and ulcerative colitis (UC). Less is known about the virome in these …
Early life dynamics of the human gut virome and bacterial microbiome in infants
The early years of life are important for immune development and influence health in
adulthood. Although it has been established that the gut bacterial microbiome is rapidly …
adulthood. Although it has been established that the gut bacterial microbiome is rapidly …