Catechol‐based biomimetic functional materials
J Sedó, J Saiz‐Poseu, F Busqué… - Advanced …, 2013 - Wiley Online Library
Catechols are found in nature taking part in a remarkably broad scope of biochemical
processes and functions. Though not exclusively, such versatility may be traced back to …
processes and functions. Though not exclusively, such versatility may be traced back to …
Metals, oxidative stress and neurodegeneration: a focus on iron, manganese and mercury
Essential metals are crucial for the maintenance of cell homeostasis. Among the 23
elements that have known physiological functions in humans, 12 are metals, including iron …
elements that have known physiological functions in humans, 12 are metals, including iron …
[HTML][HTML] Iron mediated toxicity and programmed cell death: A review and a re-examination of existing paradigms
Iron is an essential micronutrient that is problematic for biological systems since it is toxic as
it generates free radicals by interconverting between ferrous (Fe 2+) and ferric (Fe 3+) forms …
it generates free radicals by interconverting between ferrous (Fe 2+) and ferric (Fe 3+) forms …
Hydroxamate siderophores: Natural occurrence, chemical synthesis, iron binding affinity and use as Trojan horses against pathogens
Hydroxamic acids are an important class of molecules, in particular because of their metal-
chelating ability. Microorganisms, including pathogenic bacteria, use hydroxamate-based …
chelating ability. Microorganisms, including pathogenic bacteria, use hydroxamate-based …
Iron chemistry at the service of life
Iron is an essential element for almost all organisms on Earth. It is necessary for a number of
crucial processes such as hemoglobin and myoglobin transport and storage of oxygen in …
crucial processes such as hemoglobin and myoglobin transport and storage of oxygen in …
ROS-mediated iron overload injures the hematopoiesis of bone marrow by damaging hematopoietic stem/progenitor cells in mice
X Chai, D Li, X Cao, Y Zhang, J Mu, W Lu, X **ao… - Scientific Reports, 2015 - nature.com
Iron overload, caused by hereditary hemochromatosis or repeated blood transfusions in
some diseases, such as beta thalassemia, bone marrow failure and myelodysplastic …
some diseases, such as beta thalassemia, bone marrow failure and myelodysplastic …
Role of iron in the molecular pathogenesis of diseases and therapeutic opportunities
U Abbasi, S Abbina, A Gill, LE Takuechi… - ACS Chemical …, 2021 - ACS Publications
Iron is an essential mineral that serves as a prosthetic group for a variety of proteins involved
in vital cellular processes. The iron economy within humans is highly conserved in that there …
in vital cellular processes. The iron economy within humans is highly conserved in that there …
Carbon monoxide: mechanisms of action and potential clinical implications
L Rochette, Y Cottin, M Zeller, C Vergely - Pharmacology & therapeutics, 2013 - Elsevier
Small amounts of carbon monoxide (CO) are continuously produced in mammals. The
intracellular levels of CO can increase under stressful conditions following the induction of …
intracellular levels of CO can increase under stressful conditions following the induction of …
Antibacterial activities of iron chelators against common nosocomial pathogens
The activities of iron chelators (deferoxamine, deferiprone, Apo6619, and VK28) were
evaluated against type strains of Acinetobacter baumannii, Pseudomonas aeruginosa …
evaluated against type strains of Acinetobacter baumannii, Pseudomonas aeruginosa …
Hydroxypyridinones as “privileged” chelating structures for the design of medicinal drugs
MA Santos, SM Marques, S Chaves - Coordination Chemistry Reviews, 2012 - Elsevier
Hydroxypyridinones (HPs) are a family of N-heterocyclic core chelators which, based on
their specific metal-coordination, easy manipulation/derivatization and biocompatibility, have …
their specific metal-coordination, easy manipulation/derivatization and biocompatibility, have …