Epidemiological data from the Center of Disease Control (CDC) and the World Health
Organization (WHO) statistics in 2017 show that 10.0 million people around the world …

Abstract Treatment of tuberculosis (TB) has been a therapeutic challenge because of not
only the naturally high resistance level of Mycobacterium tuberculosis to antibiotics but also …

We have taken the first steps towards a complete reconstruction of the Mycobacterium
tuberculosis regulatory network based on ChIP-Seq and combined this reconstruction with …

Background Helicobacter pylori is well adapted to colonize the epithelial surface of the
human gastric mucosa and can cause persistent infections. In order to infect the gastric …

Infections with Mycobacterium tuberculosis remain a major cause of disease and death in
humans. Among the factors that contribute to M. tuberculosis's success as a pathogen is its …

The bacteriostatic and bactericidal effects and the transcriptional response of
Mycobacterium tuberculosis to representative oxidative and nitrosative stresses were …

Tuberculosis (TB) has become a curable disease, thanks to the discovery of antibiotics.
However, it has remained one of the most difficult infections to treat. Most current TB …

Neutrophils readily infiltrate infection foci, phagocytose and usually destroy microbes. In
tuberculosis (TB), a chronic pulmonary infection caused by Mycobacterium tuberculosis …

Mycobacteriophages are a diverse group of viruses infecting Mycobacterium with substantial
therapeutic potential. However, as this potential becomes realized, the molecular details of …

The study of mycobacteriophages provides insights into viral diversity and evolution, as well
as the genetics and physiology of their pathogenic hosts. Genomic characterization of 80 …