Recent advances in small molecular near-infrared fluorescence probes for a targeted diagnosis of the Alzheimer disease

Y Liu, D Zhuang, J Wang, H Huang, R Li, C Wu… - Analyst, 2022 - pubs.rsc.org
Nowadays, it is still quite challenging to achieve an early diagnosis of the Alzheimer disease
(AD) in clinics. The burgeoning near-infrared fluorescence (NIRF) imaging fulfills the …

Fluorescent probes as a tool in diagnostic and drug delivery systems

NI Georgiev, VV Bakov, KK Anichina, VB Bo**ov - Pharmaceuticals, 2023 - mdpi.com
Over the last few years, the development of fluorescent probes has received considerable
attention. Fluorescence signaling allows noninvasive and harmless real-time imaging with …

An Activatable NIR‐II Fluorescent Reporter for In Vivo Imaging of Amyloid‐β Plaques

J Miao, M Miao, Y Jiang, M Zhao, Q Li… - Angewandte Chemie …, 2023 - Wiley Online Library
Fluorescence imaging in the second near‐infrared (NIR‐II) window holds great promise for
in vivo visualization of amyloid‐β (Aβ) pathology, which can facilitate characterization and …

Early onset diagnosis in Alzheimer's disease patients via amyloid-β oligomers-sensing probe in cerebrospinal fluid

J An, K Kim, HJ Lim, HY Kim, J Shin, IW Park… - Nature …, 2024 - nature.com
Amyloid-β (Aβ) oligomers are implicated in the onset of Alzheimer's disease (AD). Herein,
quinoline-derived half-curcumin-dioxaborine (Q-OB) fluorescent probe was designed for …

Second Near‐Infrared (NIR‐II) Window for Imaging‐Navigated Modulation of Brain Structure and Function

K Zhang, FR Chen, L Wang, J Hu - Small, 2023 - Wiley Online Library
For a long time, optical imaging of the deep brain with high resolution has been a challenge.
Recently, with the advance in second near‐infrared (NIR‐II) bioimaging techniques and …

Application of biomarker-derived fluorescent probes for the detection of Alzheimer's disease

H Ding, Z Li, K Luo, Q Gong, X Tian - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by the
accumulation of beta-amyloid (Aβ) protein and neurofibrillary tangles in the brain, resulting …

Small molecular fluorescent probes for Alzheimer's disease associated active species

F Tang, K Wang, X Liu, X Zhang, W Zhou… - … A European Journal, 2023 - Wiley Online Library
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and is the main
cause of dementia worldwide. As the pathogenesis of AD is quite complicated, there is …

Polymeric dendrimers as nanocarrier vectors for neurotheranostics

H Li, S Zha, H Li, H Liu, KL Wong, AH All - Small, 2022 - Wiley Online Library
Dendrimers are polymers with well‐defined 3D branched structures that are vastly utilized in
various neurotheranostics and biomedical applications, particularly as nanocarrier vectors …

Boron-containing compounds on neurons: Actions and potential applications for treating neurodegenerative diseases

M Barrón-González, AV Montes-Aparicio… - Journal of inorganic …, 2023 - Elsevier
Boron-containing compounds (BCC) exert effects on neurons. After the expanding of both
the identification and synthesis of new BCC, novel effects in living systems have been …

Advances in targeted tracking and detection of soluble amyloid-β aggregates as a biomarker of Alzheimer's disease

H Gao, J Chen, Y Huang, R Zhao - Talanta, 2024 - Elsevier
Misfolding and aggregation of amyloid-β (Aβ) peptides are key hallmarks of Alzheimer's
disease (AD). With accumulating evidence suggesting that different Aβ species have varied …