In 2009, it was postulated that endothelial cells (ECs) would only be able to execute the
orders of growth factors if these cells would accordingly adapt their metabolism. Ten years …

The penultimate effectors of the Hippo signaling pathways YAP and TAZ, are transcriptional
co-activator proteins that play key roles in many diverse biological processes, ranging from …

Cardiovascular diseases (CVDs) are the leading cause of death and include several
vascular and cardiac disorders, such as atherosclerosis, coronary artery disease …

Angiogenesis, the formation of new blood vessels from pre-existing vasculature, is a
physiological process that begins in utero and continues throughout life in both good health …

Endothelial cells (ECs) constitute small capillary blood vessels and contribute to delivery of
nutrients, oxygen and cellular components to the local tissues, as well as to removal of …

Objectives Immune and stromal cell communication is central in the pathogenesis of
rheumatoid arthritis (RA) and psoriatic arthritis (PsA), however, the nature of these …

The senescence of alveolar type II (AT2) cells impedes self-repair of the lung epithelium and
contributes to lung injury in the setting of idiopathic pulmonary fibrosis (IPF). Yes-associated …

Spinal ependymomas are the most common spinal cord tumors in adults, but their
intratumoral cellular heterogeneity has been less studied, and how spinal microglia are …

Metabolic reprogramming of cancer is now considered a hallmark of many malignant
tumors, including breast cancer, which remains the most commonly diagnosed cancer in …

Background The conversion of fibroblasts into induced cardiomyocytes may regenerate
myocardial tissue from cardiac scar through in situ cell transdifferentiation. The efficiency …