Inflammatory mediators in the elderly
KS Krabbe, M Pedersen, H Bruunsgaard - Experimental gerontology, 2004 - Elsevier
Ageing is accompanied by 2–4-fold increases in plasma/serum levels of inflammatory
mediators such as cytokines and acute phase proteins. A wide range of factors seems to …
mediators such as cytokines and acute phase proteins. A wide range of factors seems to …
Inflammation and the degenerative diseases of aging
PL McGEER, EG McGEER - Annals of the New York Academy …, 2004 - Wiley Online Library
Chronic inflammation is associated with a broad spectrum of neurodegenerative diseases of
aging. Included are such disorders as Alzheimer's disease (AD), Parkinson's disease (PD) …
aging. Included are such disorders as Alzheimer's disease (AD), Parkinson's disease (PD) …
A meta-analysis of cytokines in Alzheimer's disease
BACKGROUND: Studies suggest that inflammation is involved in the neurodegenerative
cascade leading to Alzheimer's disease (AD) pathology and symptoms. This study sought to …
cascade leading to Alzheimer's disease (AD) pathology and symptoms. This study sought to …
Risk factors for dementia
JH Chen, KP Lin, YC Chen - Journal of the Formosan Medical Association, 2009 - Elsevier
Dementia is a complex human disease. The incidence of dementia among the elderly
population is rising rapidly worldwide. In the United States, Alzheimer's disease (AD) is the …
population is rising rapidly worldwide. In the United States, Alzheimer's disease (AD) is the …
Inflammation, autotoxicity and Alzheimer disease
PL McGeer, EG McGeer - Neurobiology of aging, 2001 - Elsevier
Neuroinflammation is a central feature of Alzheimer disease (AD). It involves an innate
immune reaction of sufficient intensity that self attack on neurons occurs. This phenomenon …
immune reaction of sufficient intensity that self attack on neurons occurs. This phenomenon …
Inflammatory processes in Alzheimer's disease
EG McGeer, PL McGeer - Progress in Neuro-Psychopharmacology and …, 2003 - Elsevier
Neuroinflammation is a characteristic of pathologically affected tissue in several
neurodegenerative disorders. These changes are particularly observed in affected brain …
neurodegenerative disorders. These changes are particularly observed in affected brain …
Polyphenols: well beyond the antioxidant capacity: gallic acid and related compounds as neuroprotective agents: you are what you eat!
M Daglia, A Di Lorenzo, SF Nabavi… - Current …, 2014 - ingentaconnect.com
Gallic acid (3, 4, 5-trihydroxybenzoic acid) is a phenolic acid widely distributed in many
different families of higher plants, both in free state, and as a part of more complex …
different families of higher plants, both in free state, and as a part of more complex …
Inflammatory cytokine levels correlate with amyloid load in transgenic mouse models of Alzheimer's disease
NS Patel, D Paris, V Mathura, AN Quadros… - Journal of …, 2005 - Springer
Background Inflammation is believed to play an important role in the pathology of
Alzheimer's disease (AD) and cytokine production is a key pathologic event in the …
Alzheimer's disease (AD) and cytokine production is a key pathologic event in the …
Molecular mechanisms of aging-associated inflammation
D Sarkar, PB Fisher - Cancer letters, 2006 - Elsevier
A direct relationship exists between aging and increasing incidences of chronic diseases. In
fact, with most age-associated diseases individuals manifest an underlying chronic …
fact, with most age-associated diseases individuals manifest an underlying chronic …
[HTML][HTML] Inflammation and neurodegenerative diseases
WST Griffin - The American journal of clinical nutrition, 2006 - Elsevier
The decline in mental fitness associated with Alzheimer disease is accompanied by physical
changes in the brain, including the development of characteristic plaques and neurofibrillary …
changes in the brain, including the development of characteristic plaques and neurofibrillary …